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Tg(Rr387-lacZ)11Jejo
Transgene Detail
Summary
Symbol: Tg(Rr387-lacZ)11Jejo
Name: transgene insertion 11, Jane E Johnson
MGI ID: MGI:7442603
Transgene: Tg(Rr387-lacZ)11Jejo  Location: unknown  
Alliance: Tg(Rr387-lacZ)11Jejo page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA)F1
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe transgene insertion contains the following elements: a SacII-SmaI restriction fragment containing sequence downstream of Atoh1 (which includes enhancer Rr387 or E0) where the last 193 bp were deleted, Hbb basal promoter, the beta-galactosidase reporter gene, and SV40 ploy(A) signal sequences. Reporter gene embryonic expression is abolished in the dorsal neural tube but still present in hindbrain. (J:60854)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:60854 Helms AW, et al., Autoregulation and multiple enhancers control Math1 expression in the developing nervous system. Development. 2000 Mar;127(6):1185-96
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory