Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Tn(Pb-Rr150101-lacZ)#Jdai
Name:	transposon insertion, Jianwu Dai
MGI ID:	MGI:7440091
Synonyms:	E1-lacZ
Transgene:	Tn(Pb-Rr150101-lacZ)#Jdai  Location: unknown
Alliance:	Tn(Pb-Rr150101-lacZ)#Jdai page

Strain of Origin:

CD-1

Allele Type:    Transposon induced (Reporter) Mutation:    Transposon insertion   Mutation details: The transgene insert contains the following elements: the 5' PiggyBAC transposon inverted repeat, Atoh1 enhancer E1, Hsp68 minimal promoter, beta-galactosidase reporter gene, SV40 early poly(A) signal sequences, and the 3' transposon inverted repeat. The transgene was injected into single-cell zygotes together with PiggyBAC transposase mRNA to facilitate integration into the genome. Several independent transgenic mouse lines were established. The reporter is expressed in the spinal cord and other neurological tissues during embryonic development. (J:332270)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:332270 Shu M, et al., Single-cell chromatin accessibility identifies enhancer networks driving gene expression during spinal cord development in mouse. Dev Cell. 2022 Dec 19;57(24):2761-2775.e6
All:	1 reference(s)