About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:71386 Ayres JA, et al., Dach: genomic characterization, evaluation as a candidate for postaxial polydactyly type a2, and developmental expression pattern of the mouse homologue. Genomics. 2001 Sep;77(1/2):18-26
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7439602
Gene symbol: Dach1
Gene name: dachshund family transcription factor 1
Antibody: anti-DACH1
Results
Specimen 4A: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: nephron epithelium Present 4A
TS24: renal convoluted tubule Present 4A
TS24: mesenchyme of metanephros Present 4A Expressed in many of the mesenchymal cells distributed throughout the cortex and medulla.
TS24: collecting duct Absent 4A

Specimen 4B: embryonic day 16.0 (more )
Structure Cell Type Level Pattern Image Note
TS24: comma-shaped body Present 4B
TS24: maturing glomerular tuft podocyte Present 4B

Specimen 4C: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: s-shaped body Present 4C Predominantly nuclear expression was seen in epithelial cells of S-shaped bodies.
TS24: renal convoluted tubule Present Regionally restricted 4C Predominantly nuclear expression was seen in longitudinal profiles of convoluted tubules.

Specimen 5B: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: forelimb bud mesenchyme Present Regionally restricted 5B Expressed in distal mesenchymal cells underlying the apical ectodermal ridge.
TS16: apical ectodermal ridge Absent 5B

Specimen 5C: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: hand epithelium Present 5C Less intense staining of the epithelium and apical ectodermal ridge.
TS20: hand mesenchyme Present Regionally restricted 5C Expressed in distal mesenchymal cells underlying the apical ectodermal ridge.

Specimen 6A: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: optic cup Present 6A
TS16: head mesenchyme Present Regionally restricted 6A Expressed in some of the mesenchymal cells surrounding the eye.

Specimen 6C: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: lens primordium Strong 6C Especially in the developing lens fibers.
TS20: eye epithelium Present Regionally restricted 6C Expressed in the ectoderm overlying the developing eye.
TS20: retina Present 6C Less intense expression.

Specimen 7A: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: inner ear epithelium Present Regionally restricted 7A Expressed in cells of the dorsomedial and dorsolateral epithelium.

Specimen 7B: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: cochlear duct Present Regionally restricted 7B Expressed in cells at each turn.

Specimen 7C: embryonic day 16.0 (more )
Structure Cell Type Level Pattern Image Note
TS24: cochlear duct Present Regionally restricted 7C Nuclear expression in the developing stria vascularis.
TS24: cochlear duct epithelium cochlear inner hair cell Present 7C Nuclear expression.
TS24: cochlear duct epithelium cochlear outer hair cell Present 7C Nuclear expression.
TS24: cochlea Present Regionally restricted 7C Expressed in mesenchymal cells underlying the organ of corti.

Specimen not shown: embryonic day 10.0 (more )
Structure Level Pattern Image Note
TS16: mesonephric tubule Present

Specimen not shown: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: mesonephric tubule Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory