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Tg(Bhlhe41-icre,-CD2)#Mbu
Transgene Detail
Summary
Symbol: Tg(Bhlhe41-icre,-CD2)#Mbu
Name: transgene insertion, Meinrad Busslinger
MGI ID: MGI:7439462
Synonyms: Bhlhe41-Cre-hCD2
Transgene: Tg(Bhlhe41-icre,-CD2)#Mbu  Location: unknown  
Alliance: Tg(Bhlhe41-icre,-CD2)#Mbu page
Transgene
origin
Strain of Origin:  (C57BL/6 CBA)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence, Recombinase)
Mutation:    Insertion
 
Tg(Bhlhe41-icre,-CD2)#Mbu expression driven by 1 gene
 
Mutation detailsBAC RP23-343I17 was used to create a transgene in which the expression of icre was under the control of the Bhlhe41 promoter by inserting icre linked by an IRES to a truncated human CD2 sequence into the Bhlhe41 locus. (J:258170)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Bhlhe41 (mouse)
Summary of all recombinase alleles driven by Bhlhe41.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:258170 Kreslavsky T, et al., Essential role for the transcription factor Bhlhe41 in regulating the development, self-renewal and BCR repertoire of B-1a cells. Nat Immunol. 2017 Apr;18(4):442-455
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory