Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Nppatm3.1(cre/ERT2)Bzsh
Name:	natriuretic peptide type A; targeted mutation 3.1, Bin Zhou
MGI ID:	MGI:7439151
Synonyms:	Nppa-CreER
Gene:	Nppa  Location: Chr4:148085179-148086531 bp, + strand  Genetic Position: Chr4, 78.66 cM
Alliance:	Nppatm3.1(cre/ERT2)Bzsh page

Germline Transmission:	Earliest citation of germline transmission: J:263128
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Nppatm3.1(cre/ERT2)Bzsh expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Nppa (MGI:97367)   Mutation details: A cDNA encoding Cre/ERT2 was inserted into the translational stop codon of Nppa gene (before 3 UTR), with a self-cleaving 2 A peptide sequence linking Nppa and cre/ERT2. (J:263128)

Activity:	Tissue activity of this recombinase allele
Driver:	Nppa (mouse) Summary of all recombinase alleles driven by Nppa. Alliance mouse Nppa gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nppa Mutation:	10 strains or lines available

Original:	J:263128 Tian X, et al., Identification of a hybrid myocardial zone in the mammalian heart after birth. Nat Commun. 2017 Jul 20;8(1):87
All:	1 reference(s)