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Gene Expression Data
Assay Details
Assay
Reference: J:187742 Mould A, et al., Blimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placenta. Genes Dev. 2012 Sep 15;26(18):2063-74
Assay type: RNA in situ
MGI Accession ID: MGI:7439132
Gene symbol: Prl2c2
Gene name: prolactin family 2, subfamily c, member 2
Probe: Prl2c cDNA
Probe preparation: Antisense RNA
Results
Specimen S2A - Prl2c2 +/+: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Regionally restricted S2A Prl2c2 +/+ Expression is seen in the secondary parietal trophoblast giant cells (P-TGCs) and spiral artery-associated trophoblast giant cells (SpA-TGCs).
TS15: secondary trophoblast giant cell Present S2A Prl2c2 +/+ Expression is seen in the secondary parietal trophoblast giant cells (P-TGCs) and spiral artery-associated trophoblast giant cells (SpA-TGCs).

Specimen S2A - Prl2c2 - -/-: embryonic day 9.5; Prdm1tm2Rob/Prdm1tm2Rob (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Regionally restricted S2A Prl2c2 -/- Expression is seen in the secondary parietal trophoblast giant cells (P-TGCs); formation of this population is unaffected in the mutants. The spiral artery-associated trophoblast giant cells (SpA-TGCs) do not form in the mutant.
TS15: secondary trophoblast giant cell Present S2A Prl2c2 -/- Expression is seen in the secondary parietal trophoblast giant cells (P-TGCs); formation of this population is unaffected in the mutants. The spiral artery-associated trophoblast giant cells (SpA-TGCs) do not form in the mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory