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Gene Expression Data
Assay Details
Assay
Reference: J:187742 Mould A, et al., Blimp1/Prdm1 governs terminal differentiation of endovascular trophoblast giant cells and defines multipotent progenitors in the developing placenta. Genes Dev. 2012 Sep 15;26(18):2063-74
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7438447
Gene symbol: Prdm1
Gene name: PR domain containing 1, with ZNF domain
Reporter: lacZ
Direct Detection
Results
Specimen 5C: embryonic day 7.5; Prdm1tm3(icre)Rob/Prdm1+ (more )
Structure Level Pattern Image Note
TS11: primordial germ cell Present 5C Expression is seen in primordial germ cells at the proximal end of the primitive streak.

Specimen 5D: embryonic day 9.5; Prdm1tm3(icre)Rob/Prdm1+ (more )
Structure Level Pattern Image Note
TS15: forelimb bud Present 5D
TS15: otocyst Present 5D
TS15: secondary heart field Present 5D

Specimen 5E: postnatal day 0; Prdm1tm3(icre)Rob/Prdm1+ (more )
Structure Cell Type Level Pattern Image Note
TS27: hair follicle dermal papilla hair follicle dermal papilla cell Present Single cells 5E
TS27: epidermis granular layer hair follicular keratinocyte Present Clusters 5E

Specimen 5F: embryonic day 10.5; Prdm1tm3(icre)Rob/Prdm1+ (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present 5F Expression is reduced in these structures.
TS17: secondary heart field Present 5F Expression is reduced in these structures.
TS17: otocyst Present 5F

Specimen 5G: embryonic day 12.5; Prdm1tm3(icre)Rob/Prdm1+ (more )
Structure Level Pattern Image Note
TS20: forelimb Present 5G
TS20: hindlimb Present 5G

Specimen 5H: embryonic day 9.5; Prdm1tm3(icre)Rob/Prdm1+ (more )
Structure Level Pattern Image Note
TS15: labyrinthine zone Absent 5H
TS15: primary trophoblast giant cell Absent 5H

Specimen 5I: embryonic day 9.5; Prdm1tm3(icre)Rob/Prdm1+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Regionally restricted 5I Expression is seen in spiral artery-associated trophoblast giant cells (SpA-TGCs) associated with maternal blood vessels.

Specimen 5J: embryonic day 9.5; Prdm1tm3(icre)Rob/Prdm1+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Regionally restricted 5J Expression is seen in glycogen trophoblasts (Gly-Ts) and spiral artery-associated trophoblast giant cells (SpA-TGCs).

Specimen 5K: embryonic day 9.5; Prdm1tm3(icre)Rob/Prdm1+ (more )
Structure Level Pattern Image Note
TS15: spongiotrophoblast Present Single cells 5K Expression is seen in a population of diploid cells.

Specimen 5L: embryonic day 9.5; Prdm1tm3(icre)Rob/Prdm1+ (more )
Structure Level Pattern Image Note
TS15: labyrinthine zone Absent 5L

Specimen 6 - Reporter: embryonic day 12.5; Prdm1tm3(icre)Rob/Prdm1+ (more )
Structure Level Pattern Image Note
TS20: spongiotrophoblast Present Regionally restricted 6A , 6C , 6D , 6_upper left Reporter Expression is seen in a population of diploid cells; in glycogen trophoblasts (Gly-Ts); in canal-associated trophoblast giant cells (C-TGCs); and in spiral artery-associated trophoblast giant cells (SpA-TGCs) associated with maternal blood vessels.
TS20: labyrinthine zone Absent 6B , 6_upper left Reporter

Specimen S4C: embryonic day 12.5; Prdm1tm3(icre)Rob/Prdm1+ (more )
Structure Level Pattern Image Note
TS20: spongiotrophoblast Present Regionally restricted S4C Expression is seen in glycogen trophoblasts (Gly-Ts) and canal-associated trophoblast giant cells (C-TGCs).


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory