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Gene Expression Data
Assay Details
Assay
Reference: J:194470 Davis RB, et al., BRG1 promotes COUP-TFII expression and venous specification during embryonic vascular development. Development. 2013 Mar;140(6):1272-81
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7438440
Gene symbol: Nr2f2
Gene name: nuclear receptor subfamily 2, group F, member 2
Antibody: anti-COUP-TFII (PP-H7147-00)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4A: embryonic day 10.5 (more )
Note: Double labeled: green - Nr2f2; red - Pecam1 (assay MGI:7438426).
Structure Cell Type Level Pattern Image Note
TS17: umbilical vein endothelial cell of umbilical vein Present 4A
Specimen 4B: embryonic day 10.5; Smarca4tm1.2Pcn/Smarca4tm1.2Pcn, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant. Double labeled: green - Nr2f2; red - Pecam1 (assay MGI:7438426).
Structure Cell Type Level Pattern Image Note
TS17: umbilical vein endothelial cell of umbilical vein Trace 4B Expression was significantly diminished in the venous endothelial cells.
Specimen 4C: embryonic day 9.75 (more )
Note: Double labeled: green - Nr2f2; red - Pecam1 (assay MGI:7438426).
Structure Cell Type Level Pattern Image Note
TS16: cardinal vein vein endothelial cell Present 4C
Specimen 4D: embryonic day 9.75; Smarca4tm1.2Pcn/Smarca4tm1.2Pcn, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant. Double labeled: green - Nr2f2; red - Pecam1 (assay MGI:7438426).
Structure Cell Type Level Pattern Image Note
TS16: cardinal vein vein endothelial cell Ambiguous 4D Expression was downregulated in the cardinal vein endothelial cells.
Specimen S5G: embryonic day 10.5 (more )
Note: Double labeled: green - Nr2f2; red - Pecam1 (assay MGI:7438426).
Structure Cell Type Level Pattern Image Note
TS17: umbilical vein endothelial cell of umbilical vein Present S5G
Specimen S5H: embryonic day 10.5; Ctnnb1tm2Kem/Ctnnb1tm2Kem, Tg(Tek-cre)1Ywa/0 (more )
Note: Conditional mutant. Double labeled: green - Nr2f2; red - Pecam1 (assay MGI:7438426).
Structure Cell Type Level Pattern Image Note
TS17: umbilical vein endothelial cell of umbilical vein Present S5H Comparable expression levels of Nr2f2 were seen in both control and Catnb<fl/fl>;Tie2-Cre+ umbilical veins.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory