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Gene Expression Data
Assay Details
Assay
Reference: J:302867 Laurin M, et al., The Rac-specific exchange factors Dock1 and Dock5 are dispensable for the establishment of the glomerular filtration barrier in vivo. Small GTPases. 2013 Oct-Dec;4(4):221-30
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7438407
Gene symbol: Dock1
Gene name: dedicator of cytokinesis 1
Antibody: Anti-Dock180 (C-19 sc-6167)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 1B +/+: embryonic day 16.5 (more )
Note: Double labeled: red - Dock1; green - Wt1 (assay MGI:7438408).
Structure Level Pattern Image Note
TS24: glomerular capillary system of maturing glomerular tuft Strong 1B Dock1 +/+ , 1B Merge +/+
TS24: maturing glomerular tuft Strong 1B Dock1 +/+ , 1B Merge +/+
Specimen 1B -/-: embryonic day 16.5; Dock1tm2.1Jfco/Dock1tm2.1Jfco (more )
Note: Double labeled: red - Dock1; green - Wt1 (assay MGI:7438408).
Structure Level Pattern Image Note
TS24: glomerular capillary system of maturing glomerular tuft Absent 1B Merge -/- , 1B Dock1 -/-
TS24: maturing glomerular tuft Absent 1B Merge -/- , 1B Dock1 -/-
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory