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Tg(RP11-94J18/RP11-662G11)BMym
Transgene Detail
Summary
Symbol: Tg(RP11-94J18/RP11-662G11)BMym
Name: transgene insertion B, Masayuki Yamamoto
MGI ID: MGI:7438188
Synonyms: 3q21q26 Tg
Transgene: Tg(RP11-94J18/RP11-662G11)BMym  Location: unknown  
Alliance: Tg(RP11-94J18/RP11-662G11)BMym page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe transgene contains linking two BAC clones (RP11-662G11 and RP11-94J18) containing the 3q21 and 3q26 sequences, respectively, recapitulating the genomic content of the inv(3)(q21;q26) genomic region identified in MOLM-1 cells from a patient with megakaryoblastic leukemia. (J:210807)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:210807 Yamazaki H, et al., A remote GATA2 hematopoietic enhancer drives leukemogenesis in inv(3)(q21;q26) by activating EVI1 expression. Cancer Cell. 2014 Apr 14;25(4):415-27
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory