Tg(HLA-B*0801/H2-Kb)B*0801Fal
Transgene Detail
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| Symbol: |
Tg(HLA-B*0801/H2-Kb)B*0801Fal |
| Name: |
transgene insertion B*0801, Francois A Lemonnier |
| MGI ID: |
MGI:7437942 |
| Synonyms: |
HLA-B*08:01 |
| Transgene: |
Tg(HLA-B*0801/H2-Kb)B*0801Fal Location: unknown Genetic Position: ChrUN, Syntenic
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| Alliance: |
Tg(HLA-B*0801/H2-Kb)B*0801Fal page
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| Strain of Origin: |
C57BL/6 x SJL
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: The transgene contains HLA-A*02:01 promotor and the coding sequence of a chimeric molecule composed of the HLA-A*02:01 leader segment, the human beta2-m in its mature form, a 15-aa (GGGGS) x 3 linker peptide, the alpha1 alpha2 HLA class I domains, and the H-2 Db alpha3 to cytoplasmic domains.
(J:205453)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:205453 Boucherma R, et al., HLA-A*01:03, HLA-A*24:02, HLA-B*08:01, HLA-B*27:05, HLA-B*35:01, HLA-B*44:02, and HLA-C*07:01 monochain transgenic/H-2 class I null mice: novel versatile preclinical models of human T cell responses. J Immunol. 2013 Jul 15;191(2):583-93 |
| All: |
1 reference(s) |
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Analysis Tools
