Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Twist2tm1(cre/ERT2)Eno
Name:	twist basic helix-loop-helix transcription factor 2; targeted mutation 1, Eric N Olson
MGI ID:	MGI:7437699
Synonyms:	Tw2-CreERT2, Tw2-CreERT2-neo
Gene:	Twist2  Location: Chr1:91729183-91775750 bp, + strand  Genetic Position: Chr1, 46.24 cM
Alliance:	Twist2tm1(cre/ERT2)Eno page

Germline Transmission:	Earliest citation of germline transmission: J:246973
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEv

Allele Type:    Targeted (Inducible, Recombinase) Mutations:    Insertion, Intragenic deletion   Twist2tm1(cre/ERT2)Eno expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Twist2 (MGI:104685)     A CreERT2-Frt-Neo-Frt expression cassette was inserted to replace exon 1 of the Twist2 gene. (J:246973)

Activity:	Tissue activity of this recombinase allele
Driver:	Twist2 (mouse) Summary of all recombinase alleles driven by Twist2. Comparative matrix view of recombinase activities Alliance mouse Twist2 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Twist2 Mutation:	10 strains or lines available

Original:	J:246973 Liu N, et al., A Twist2-dependent progenitor cell contributes to adult skeletal muscle. Nat Cell Biol. 2017 Mar;19(3):202-213
All:	2 reference(s)