Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Sfrp5tm1.1(cre)Kkb
Name:	secreted frizzled-related sequence protein 5; targeted mutation 1.1, Hiroki Kokubo
MGI ID:	MGI:7437537
Synonyms:	Sfrp5-Cre
Gene:	Sfrp5  Location: Chr19:42186410-42190691 bp, - strand  Genetic Position: Chr19, 35.93 cM, cytoband D1
Alliance:	Sfrp5tm1.1(cre)Kkb page

Germline Transmission:	Earliest citation of germline transmission: J:245018
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Recombinase) Mutations:    Insertion, Intragenic deletion   Sfrp5tm1.1(cre)Kkb expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Sfrp5 (MGI:1860298)   Mutation details: A targeting vector consist of a cassette containing Cre-recombinase genes with frt-PGK-neomycin (neo)-bpA-frt was used for homologous recombination to replace the exon 1 of the Sfrp5 gene in ES cells. Frt-neo was then removed by crossing with Rosa-Flp mice. (J:245018)

Activity:	Tissue activity of this recombinase allele
Driver:	Sfrp5 (mouse) Summary of all recombinase alleles driven by Sfrp5. Comparative matrix view of recombinase activities Alliance mouse Sfrp5 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sfrp5 Mutation:	25 strains or lines available

Original:	J:245018 Fujii M, et al., Sfrp5 identifies murine cardiac progenitors for all myocardial structures except for the right ventricle. Nat Commun. 2017 Mar 13;8:14664
All:	2 reference(s)