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Gene Expression Data
Assay Details
Assay
Reference: J:252976 Shin JO, et al., Temporal and spatial expression patterns of Hedgehog receptors in the developing inner and middle ear. Int J Dev Biol. 2017;61(8-9):557-563
Assay type: RNA in situ
MGI Accession ID: MGI:7437508
Gene symbol: Cdon
Gene name: cell adhesion molecule-related/down-regulated by oncogenes
Probe: Cdon cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1D: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: neural tube Present Regionally restricted 1D Expression was detected in the dorsal tip of the neural tube.
TS15: otocyst Present Regionally restricted 1D Expression was detected on the dorsolateral side of the otocyst.

Specimen 1I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 1I Expression was detected in the dorsal tip of the neural tube.
TS17: otocyst Present Regionally restricted 1I Expression was detected on the dorsolateral side of the otocyst.

Specimen 2E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS20: inner ear epithelium Present Graded 2E Expression was detected in a gradient (stronger dorsally and weaker ventrally).
TS20: inner ear mesenchyme Present Graded 2E Expression was detected in a gradient (stronger dorsally and weaker ventrally).

Specimen 2K: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS20: inner ear epithelium Present Graded 2K Expression was detected in a gradient (stronger dorsally and weaker ventrally).
TS20: inner ear mesenchyme Present Graded 2K Expression was detected in a gradient (stronger dorsally and weaker ventrally).
TS20: semicircular canal Present Regionally restricted 2K Expression was detected in the cristae.

Specimen 2Q: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS20: inner ear epithelium Present Graded 2Q Expression was detected in a gradient (stronger dorsally and weaker ventrally).
TS20: inner ear mesenchyme Present Graded 2Q Expression was detected in a gradient (stronger dorsally and weaker ventrally).

Specimen 2W: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS20: inner ear epithelium Present Graded 2W Expression was detected in a gradient (stronger dorsally and weaker ventrally).
TS20: inner ear mesenchyme Present Graded 2W Expression was detected in a gradient (stronger dorsally and weaker ventrally).
TS20: vestibulo-cochlear ganglion Absent 2W

Specimen 4I: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: inner ear Present Regionally restricted 4I Expression was not detected in the sensory organs, but was expressed in most of the non-sensory regions, with the exception of the endolymphatic duct and Reissner's membrane.

Specimen 4J: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: inner ear Present Regionally restricted 4J' , 4J Expression was not detected in the sensory organs, but was expressed in most of the non-sensory regions, with the exception of the endolymphatic duct and Reissner's membrane.
TS23: cochlea Present Graded 4J Graded expression pattern was stronger at the base and weaker toward the apex.

Specimen 5G: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: inner ear vestibular component Present Regionally restricted 5G' , 5G , 5G'' Expression was detected in the non-sensory regions of the vestibule.

Specimen 5H: postnatal day 0 (more )
Structure Cell Type Level Pattern Image Note
TS27: external spiral sulcus Present Regionally restricted 5H'' , 5H , 5H' Expression was detected in outer sulcus cells derived from the lesser epithelial ridge.
TS27: cochlea epithelium strial marginal cell Present 5H' , 5H , 5H''

Specimen 6E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: middle ear Present Regionally restricted 6E Expression was detected in middle ear joints and annular ligaments.
TS23: stapes Present Regionally restricted 6E Expression was detected in stapedial footplate.

Specimen 6K: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: middle ear Present Regionally restricted 6K Expression was detected in middle ear joints.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory