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Gene Expression Data
Assay Details
Assay
Reference: J:51497 Mariano JM, et al., Concurrent and distinct transcription and translation of transforming growth factor-beta type I and type II receptors in rodent embryogenesis. Int J Dev Biol. 1998 Nov;42(8):1125-36
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7437503
Gene symbol: Tgfbr2
Gene name: transforming growth factor, beta receptor II
Antibody: anti-TGF-beta RII (L-21)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 3E embryo: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: ectoplacental cone Present 3E
TS15: trophoblast giant cell Present 3E
Specimen 3E maternal: postnatal adult (more )
Structure Level Pattern Image Note
TS28: decidua Present 3E
Specimen 3F embryo: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: ectoplacental cone Present Clusters 3F
TS15: trophoblast giant cell Present Clusters 3F
Specimen 3F maternal: postnatal adult (more )
Structure Level Pattern Image Note
TS28: decidua Present 3F
Specimen 3H: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo ectoderm Present 3H
TS15: mesenchyme derived from splanchnopleure Present 3H
TS15: trunk paraxial mesenchyme Present 3H
TS15: neural tube Present 3H There is a discrepancy between the figure legend and the table, the figure legend indicates expression in the neural tube is present but the table states expression is absent.
Specimen 4E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: common atrial chamber cardiac muscle Present 4E
TS15: primitive ventricle cardiac muscle Present 4E
TS15: trunk mesenchyme Trace 4E
Specimen 4F: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: common atrial chamber cardiac muscle Present 4F
TS15: primitive ventricle cardiac muscle Present 4F
Specimen 4G: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: common atrial chamber cardiac muscle Present 4G
TS17: primitive ventricle cardiac muscle Present 4G
Specimen 4H: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: atrium cardiac muscle Very strong 4H
TS20: ventricle cardiac muscle Very strong 4H
Specimen 5E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: dorsal root ganglion Weak 5E
Specimen 5F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Weak 5F
TS20: skeletal musculature Weak 5F
TS20: vertebral cartilage condensation Weak 5F
Specimen 5G: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: dorsal root ganglion sensory neuron Very strong 5G
TS21: vertebral cartilage condensation Present 5G
Specimen 5J: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: lung epithelium Weak 5J
TS17: lung mesenchyme Weak 5J There is a discrepancy between the figure legend and the table, the figure legend indicates expression in the mesenchyme is weak but the table states it is absent.
Specimen 5L: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: bronchiole epithelium Very strong 5L
TS22: lung vascular element Moderate Regionally restricted 5L Expression is in lung arteries.
TS22: lung mesenchyme Absent 5L There is a discrepancy between the figure legend and the table, the figure legend indicates expression in the mesenchyme is absent but the table states there is faint expression.
Specimen Table 1 E8 embryo: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: ectoplacental cone Weak
TS13: primitive ventricle cardiac muscle Weak
TS13: trophoblast giant cell Weak
TS13: embryo mesenchyme Trace
TS13: yolk sac Trace
TS13: arterial blood vessel Absent
TS13: common atrial chamber cardiac muscle Absent
TS13: neural tube Absent
Specimen Table 1 E8 maternal: postnatal adult (more )
Structure Level Pattern Image Note
TS28: decidua Weak
Specimen Table 1 E9 embryo: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: common atrial chamber cardiac muscle Weak
TS15: ectoplacental cone Weak
TS15: primitive ventricle cardiac muscle Weak
TS15: trophoblast giant cell Weak
TS15: embryo mesenchyme Trace
TS15: yolk sac Trace
TS15: arterial blood vessel Absent
TS15: neural tube Absent There is a discrepancy between the figure legend and the table, the figure legend indicates expression in the neural tube is present but the table states expression is absent.
Specimen Table 1 E9 maternal: postnatal adult (more )
Structure Level Pattern Image Note
TS28: decidua Present
Specimen Table 1 E10: embryonic day 10.5 (more )
Structure Cell Type Level Pattern Image Note
TS17: common atrial chamber cardiac muscle Moderate
TS17: primitive ventricle cardiac muscle Moderate
TS17: surface ectoderm Moderate
TS17: yolk sac Moderate
TS17: nerve Moderate Expression is in projecting nerves.
TS17: arterial blood vessel Weak
TS17: brain Weak
TS17: embryo mesenchyme Weak
TS17: neural tube Weak
TS17: bronchus epithelium Trace
TS17: gut epithelium Trace
TS17: dorsal root ganglion Absent
TS17: gut mesenchyme Absent
TS17: 1st branchial arch mandibular component mesenchyme Absent Absent in the lower jaw mesenchyme.
TS17: liver hepatocyte Absent
TS17: liver megakaryocyte Absent
TS17: lung mesenchyme Absent There is a discrepancy between the figure legend and the table, the figure legend indicates expression in the mesenchyme is weak but the table states it is absent.
Specimen Table 1 E11: embryonic day 11.5 (more )
Structure Cell Type Level Pattern Image Note
TS19: atrium cardiac muscle Moderate
TS19: embryo mesenchyme Moderate
TS19: surface ectoderm Moderate
TS19: ventricle cardiac muscle Moderate
TS19: nerve Moderate Expression is in projecting nerves.
TS19: jaw primordium epithelium Moderate Expression is in the lower jaw.
TS19: nasal epithelium Moderate
TS19: arterial blood vessel Present
TS19: future spinal cord Present
TS19: neural tube Present
TS19: brain Weak
TS19: bronchus epithelium Weak
TS19: intestine epithelium Weak
TS19: jaw primordium mesenchyme Weak Expression is in the lower jaw.
TS19: dorsal root ganglion Trace
TS19: lung mesenchyme Trace
TS19: future pituitary Absent
TS19: intestine mesenchyme Absent
TS19: pre-cartilage condensation Absent
TS19: liver hepatocyte Absent
TS19: liver megakaryocyte Absent
Specimen Table 1 E12: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: adrenal primordium Moderate
TS20: arterial blood vessel Moderate
TS20: brain Moderate
TS20: embryo mesenchyme Moderate
TS20: gut muscularis Moderate
TS20: nasal epithelium Moderate
TS20: skin Moderate
TS20: spinal cord Moderate
TS20: ventricle cardiac muscle Moderate
TS20: nerve Moderate Expression is in projecting nerves.
TS20: jaw primordium epithelium Moderate Expression is in the lower jaw.
TS20: atrium cardiac muscle Present
TS20: choroid plexus Present
TS20: jaw primordium mesenchyme Present Expression is in the lower jaw.
TS20: bronchus epithelium Weak
TS20: dorsal root ganglion Weak
TS20: intestine epithelium Weak
TS20: intestine mesenchyme Weak
TS20: pancreas Weak Regionally restricted Expression is in the endocrine pancreas and is absent in the exocrine pancreas.
TS20: liver hepatocyte Weak
TS20: liver megakaryocyte Weak
TS20: pre-cartilage condensation Trace
TS20: skeletal muscle Trace
TS20: cartilage chondrocyte Trace
TS20: metanephros Trace Regionally restricted Expression is in the metanephric duct and its derivatives.
TS20: lung mesenchyme Absent
TS20: pituitary gland Absent
Specimen Table 1 E13: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: dorsal root ganglion Very strong
TS21: spinal cord Very strong
TS21: ventricle cardiac muscle Very strong
TS21: adrenal gland Strong
TS21: atrium cardiac muscle Strong
TS21: brain Strong
TS21: choroid plexus Strong
TS21: lower jaw epithelium Strong
TS21: arterial blood vessel Moderate
TS21: bronchus epithelium Moderate
TS21: embryo mesenchyme Moderate
TS21: intestine epithelium Moderate
TS21: intestine muscularis Moderate
TS21: nasal epithelium Moderate
TS21: skeletal muscle Moderate
TS21: skin Moderate
TS21: nerve Moderate Expression is in projecting nerves.
TS21: pancreas Moderate Regionally restricted Expression is in the endocrine pancreas.
TS21: liver hepatocyte Moderate
TS21: liver megakaryocyte Moderate
TS21: lower jaw mesenchyme Present
TS21: metanephros Present Regionally restricted Expression is in the metanephric duct and its derivatives.
TS21: pituitary gland Weak
TS21: intestine mesenchyme Trace
TS21: lung epithelium Trace
TS21: perichondrium Trace
TS21: cartilage chondrocyte Trace
TS21: smooth muscle tissue Trace Regionally restricted Expression is in airway smooth muscle.
TS21: lung mesenchyme Absent
Specimen Table 1 E14: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: nasal epithelium Very strong
TS22: spinal cord Very strong
TS22: brain Strong
TS22: choroid plexus Strong
TS22: dorsal root ganglion Strong
TS22: lower jaw epithelium Strong
TS22: adrenal gland Moderate
TS22: atrium cardiac muscle Moderate
TS22: intestine epithelium Moderate
TS22: intestine muscularis Moderate
TS22: skeletal muscle Moderate
TS22: skin Moderate
TS22: trachea epithelium Moderate
TS22: ventricle cardiac muscle Moderate
TS22: nerve Moderate Expression is in projecting nerves.
TS22: arterial blood vessel Present
TS22: vibrissa follicle Present
TS22: cartilage chondrocyte Present Regionally restricted Expression is in chondrocytes and in hypertrophic cartilage.
TS22: liver hepatocyte Present
TS22: liver megakaryocyte Present
TS22: metanephros Present Regionally restricted Expression is in the metanephric duct and its derivatives.
TS22: bronchus epithelium Weak
TS22: pancreas Weak
TS22: perichondrium Weak
TS22: pituitary gland Weak
TS22: smooth muscle tissue Weak Regionally restricted Expression is in airway smooth muscle.
TS22: intestine mesenchyme Trace
TS22: lower jaw mesenchyme Trace
TS22: lung epithelium Trace
TS22: maturing glomerular tuft Trace
TS22: lung mesenchyme Trace There is a discrepancy between the figure legend and the table, the figure legend indicates expression in the mesenchyme is absent but the table states there is faint expression.
TS22: thymus primordium Absent
Specimen Table 1 E15: embryonic day 15.5 (more )
Structure Cell Type Level Pattern Image Note
TS23: spinal cord Very strong
TS23: trachea epithelium Very strong
TS23: blood Very strong Regionally restricted Expression is in forming blood cells in the liver.
TS23: adrenal gland Moderate
TS23: atrium cardiac muscle Moderate
TS23: brain Moderate
TS23: choroid plexus Moderate
TS23: dorsal root ganglion Moderate
TS23: skeletal muscle Moderate
TS23: skin Moderate
TS23: stomach epithelium Moderate
TS23: ventricle cardiac muscle Moderate
TS23: arterial blood vessel Present
TS23: intestine epithelium Present
TS23: intestine muscularis Present
TS23: lower jaw epithelium Present
TS23: nasal epithelium Present
TS23: cartilage chondrocyte Present Regionally restricted Expression is in chondrocytes and in hypertrophic cartilage.
TS23: nerve Weak Expression is in projecting nerves.
TS23: endocrine pancreas Weak
TS23: pancreas Weak
TS23: vibrissa follicle Weak
TS23: smooth muscle tissue Weak Regionally restricted Expression is in airway smooth muscle.
TS23: bronchus epithelium Trace
TS23: intestine mesenchyme Trace
TS23: lower jaw mesenchyme Trace
TS23: lung epithelium Trace
TS23: maturing glomerular tuft Trace
TS23: perichondrium Trace
TS23: pituitary gland Trace
TS23: liver hepatocyte Trace Some forming blood cells had intense staining.
TS23: liver megakaryocyte Trace Some forming blood cells had intense staining.
TS23: metanephros Trace Regionally restricted Expression is in the metanephric duct and its derivatives.
TS23: lung mesenchyme Absent
TS23: thymus primordium Absent
Specimen Table 1 E16: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: bronchus epithelium Very strong
TS24: spinal cord Very strong
TS24: trachea epithelium Very strong
TS24: intestine epithelium Strong
TS24: skeletal muscle Strong
TS24: skin Strong
TS24: arterial blood vessel Moderate
TS24: atrium cardiac muscle Moderate
TS24: brain Moderate
TS24: choroid plexus Moderate
TS24: dorsal root ganglion Moderate
TS24: intestine muscularis Moderate
TS24: ventricle cardiac muscle Moderate
TS24: lower jaw epithelium Present
TS24: lung mesenchyme Present
TS24: nasal epithelium Present
TS24: vibrissa follicle Present
TS24: respiratory system smooth muscle Present Regionally restricted Expression is in airway smooth muscle.
TS24: endocrine pancreas Weak
TS24: pancreas Weak
TS24: nerve Weak Expression is in projecting nerves.
TS24: thymus Weak Expression is in projecting nerves.
TS24: cartilage chondrocyte Weak Regionally restricted Expression is in chondrocytes and in hypertrophic cartilage.
TS24: liver hepatocyte Weak
TS24: liver megakaryocyte Weak
TS24: metanephros Weak Regionally restricted Expression is in the metanephric duct and is trace in its derivatives.
TS24: alveolus epithelium Trace
TS24: intestine mesenchyme Trace
TS24: maturing glomerular tuft Trace
TS24: perichondrium Trace
TS24: adrenal gland Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory