Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Mobp-icre/ERT2)8Dbe
Name:	transgene insertion 8, Dwight E Bergles
MGI ID:	MGI:7434619
Synonyms:	Mobp-iCreER
Transgene:	Tg(Mobp-icre/ERT2)8Dbe  Location: unknown
Alliance:	Tg(Mobp-icre/ERT2)8Dbe page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Mobp-icre/ERT2)8Dbe expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Mobp (MGI:108511)   Mutation details: The iCreERT2 sequence was inserted into pBACe3.6_RP23-127H7. Five founders were analyzed. Lines 8 and 16 with the highest tamoxifen-dependent recombination efficiency were selected and maintained as conditional cre lines. (J:333154)

Activity:	Tissue activity of this recombinase allele
Driver:	Mobp (mouse) Summary of all recombinase alleles driven by Mobp. Alliance mouse Mobp gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:333154 Heo D, et al., Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43. Elife. 2022 Mar 21;11:e75230
All:	1 reference(s)