Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Mobp-icre/ERT2)10Dbe
Name:	transgene insertion 10, Dwight E Bergles
MGI ID:	MGI:7434613
Synonyms:	Mobp-iCre
Transgene:	Tg(Mobp-icre/ERT2)10Dbe  Location: unknown
Alliance:	Tg(Mobp-icre/ERT2)10Dbe page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Constitutively active, Recombinase) Mutation:    Insertion   Tg(Mobp-icre/ERT2)10Dbe expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Mobp (MGI:108511)   Mutation details: The iCreERT2 sequence was inserted into pBACe3.6_RP23-127H7. Five founders were analyzed. In one line, line 10, the Cre recombination was independent of the tamoxifen injection and designated as a constitutively active cre line. (J:333154)

Activity:	Tissue activity of this recombinase allele
Driver:	Mobp (mouse) Summary of all recombinase alleles driven by Mobp. Comparative matrix view of recombinase activities Alliance mouse Mobp gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:333154 Heo D, et al., Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43. Elife. 2022 Mar 21;11:e75230
All:	1 reference(s)