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Gene Expression Data
Assay Details
Assay
Reference: J:138922 Uez N, et al., Sall4 isoforms act during proximal-distal and anterior-posterior axis formation in the mouse embryo. Genesis. 2008 Sep 9;46(9):463-477
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7434360
Gene symbol: Sall4
Gene name: spalt like transcription factor 4
Reporter: lacZ
Direct Detection
Results
Specimen 2a: embryonic day 5.0; Sall4Gt(W097E01)Flo/Sall4+ (more )
Structure Level Pattern Image Note
TS7: extraembryonic visceral endoderm Present 2a
TS7: extraembryonic ectoderm Absent 2a

Specimen 2b: embryonic day 5.75; Sall4Gt(W097E01)Flo/Sall4+ (more )
Structure Level Pattern Image Note
TS7: epiblast Present Regionally restricted 2b Expression was detected in proximal epiblast.
TS7: extraembryonic ectoderm Absent 2b

Specimen 2c: embryonic day 6.0; Sall4Gt(W097E01)Flo/Sall4+ (more )
Structure Level Pattern Image Note
TS8: epiblast Present Regionally restricted 2c Expression spread distally in the epiblast at E6.0.
TS8: extraembryonic ectoderm Absent 2c

Specimen 2d: embryonic day 5.0; Sall4Gt(RRC044)Byg/Sall4+ (more )
Note: It is possible the specimen carries the Sall4Gt(XE027)Byg allele.
Structure Level Pattern Image Note
TS7: embryo Present Ubiquitous 2d
TS7: extraembryonic component Present Ubiquitous 2d

Specimen 2f: embryonic day 7.5; Sall4Gt(W097E01)Flo/Sall4+ (more )
Structure Level Pattern Image Note
TS11: embryonic visceral endoderm Present 2f
TS11: parietal endoderm Present 2f
TS11: extraembryonic ectoderm Absent 2f

Specimen 2g upper: embryonic day 7.5; Sall4Gt(W097E01)Flo/Sall4+ (more )
Structure Level Pattern Image Note
TS11: parietal endoderm Present 2g upper
TS11: extraembryonic ectoderm Absent 2g upper

Specimen 2g lower: embryonic day 7.5; Sall4Gt(W097E01)Flo/Sall4+ (more )
Structure Level Pattern Image Note
TS11: embryonic visceral endoderm Present 2g lower

Specimen 2i: embryonic day 11.5; Sall4Gt(W097E01)Flo/Sall4+ (more )
Structure Level Pattern Image Note
TS19: midbrain Present Regionally restricted 2i Expression was detected in the dorsal tectum and ventral midbrain.
TS19: forebrain Absent 2i
TS19: apical ectodermal ridge Present 2i
TS19: future spinal cord Present 2i
TS19: somite Absent 2i
TS19: tail Present Regionally restricted 2i Expression was detected in the tail tip.

Specimen 2j: embryonic day 11.5; Sall4Gt(RRC044)Byg/Sall4+ (more )
Note: It is possible the specimen carries the Sall4Gt(XE027)Byg allele.
Structure Level Pattern Image Note
TS19: midbrain Present Regionally restricted 2j Beta-galactosidase activity in the dorsal midbrain differed compared with the Sall4-1a line.
TS19: forebrain Present 2j Sall4-1a,b line showed additional beta-galactosidase activity in the forebrain compared with the Sall4-1a line.
TS19: limb Present Widespread 2j
TS19: future spinal cord Present 2j
TS19: somite Present 2j
TS19: tail Strong Regionally restricted 2j Beta-galactosidase activity in the tail tip was more intense compared with the Sall4-1a line.

Specimen 2k: embryonic day 11.5; Sall4Gt(W097E01)Flo/Sall4+ (more )
Structure Level Pattern Image Note
TS19: midbrain Present Regionally restricted 2k Expression was detected in the dorsal tectum and ventral midbrain.
TS19: forebrain Absent 2k
TS19: apical ectodermal ridge Present 2k
TS19: future spinal cord Present 2k
TS19: somite Absent 2k
TS19: tail Present Regionally restricted 2k Expression was detected in the tail tip.

Specimen 2l: embryonic day 11.5; Sall4Gt(RRC044)Byg/Sall4+ (more )
Note: It is possible the specimen carries the Sall4Gt(XE027)Byg allele.
Structure Level Pattern Image Note
TS19: midbrain Present Regionally restricted 2l Beta-galactosidase activity in the dorsal midbrain differed compared with the Sall4-1a line.
TS19: forebrain Present 2l Sall4-1a,b line showed additional beta-galactosidase activity in the forebrain compared with the Sall4-1a line.
TS19: limb Present Widespread 2l
TS19: future spinal cord Present 2l
TS19: somite Present 2l
TS19: tail Strong Regionally restricted 2l Beta-galactosidase activity in the tail tip was more intense compared with the Sall4-1a line.

Specimen 8a: embryonic day 9.5; Sall4Gt(W097E01)Flo/Sall4+ (more )
Structure Level Pattern Image Note
TS15: embryo Present 8a


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory