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Gene Expression Data
Assay Details
Assay
Reference: J:318994 Yang J, et al., Localization of Beclin1 in mouse developing tooth germs: possible implication of the interrelation between autophagy and apoptosis. J Mol Histol. 2013 Dec;44(6):619-27
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7433060
Gene symbol: Becn1
Gene name: beclin 1, autophagy related
Antibody: anti-Beclin1
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 1a: embryonic day 13.5 (more )
Note: Bud stage of tooth development.
Structure Level Pattern Image Note
TS21: lower jaw molar epithelium Present Regionally restricted 1a Expression is the epithelium bud that facing the oral cavity and invades into the tip of the bud.
TS21: lower jaw molar mesenchyme Present Regionally restricted 1a Expression is in the condensed mesenchyme around the epithelial bud.
TS21: oral epithelium Present 1a

Specimen 1b: embryonic day 14.5 (more )
Note: Cap stage of tooth development.
Structure Level Pattern Image Note
TS22: cap stage tooth Present Regionally restricted 1b Expression is in the inner and outer enamel epithelium.
TS22: lower jaw molar epithelium Present Regionally restricted 1b Expression is in the inner and outer enamel epithelium.
TS22: primary enamel knot Present 1b
TS22: stellate reticulum Present 1b

Specimen 1c: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: palatal shelf epithelium Present Regionally restricted 1c Expression is in the non-transitional epithelial island of the medial epithelial seam at the midline.

Specimen 1d: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: Meckel's cartilage Present 1d

Specimen 1e: embryonic day 16.5 (more )
Note: Early bell stage of tooth development.
Structure Cell Type Level Pattern Image Note
TS24: lower jaw skeleton osteoblast Strong Single cells 1e , 1e' Expression is in osteoblasts in the alveolar bone.
TS24: early bell stage tooth Present 1e' , 1e
TS24: inner enamel epithelium Present 1e' , 1e
TS24: lower jaw molar dental lamina Present 1e' , 1e
TS24: lower jaw molar enamel organ Present 1e' , 1e
TS24: mandible Present 1e' , 1e
TS24: outer enamel epithelium Present 1e' , 1e
TS24: stellate reticulum Present 1e' , 1e
TS24: stratum intermedium Present 1e' , 1e

Specimen 1f: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: nasal cartilage Present 1f
TS24: nasal cavity mucosa Present 1f

Specimen 1g: embryonic day 18.5 (more )
Note: Late bell stage of tooth development.
Structure Level Pattern Image Note
TS26: inner enamel epithelium Present 1g' , 1g'' , 1g
TS26: molar dental lamina Present 1g' , 1g'' , 1g
TS26: outer enamel epithelium Present 1g' , 1g'' , 1g
TS26: stellate reticulum Present 1g' , 1g'' , 1g
TS26: stratum intermedium Present 1g' , 1g'' , 1g

Specimen 2a: postnatal day 1.5 (more )
Structure Cell Type Level Pattern Image Note
TS27: molar dental pulp odontoblast Present Regionally restricted 2a'' , 2a' , 2a Expression is in the polarizing and differentiated odontoblasts.
TS27: lower jaw molar enamel organ ameloblast Present Regionally restricted 2a , 2a'' , 2a' Expression is in differentiating ameloblasts.
TS27: stellate reticulum Present Single cells 2a' , 2a , 2a'' There are scattered positive cells in the stellate reticulum.
TS27: outer enamel epithelium Present 2a , 2a' , 2a''
TS27: stratum intermedium Present 2a , 2a' , 2a''

Specimen 2b: postnatal day 5.5 (more )
Structure Cell Type Level Pattern Image Note
TS28: outer enamel epithelium Present 2b' , 2b'' , 2b
TS28: stellate reticulum Present 2b' , 2b'' , 2b
TS28: stratum intermedium Present 2b' , 2b'' , 2b
TS28: lower jaw molar enamel organ ameloblast Present 2b' , 2b , 2b''
TS28: molar dental pulp odontoblast Present 2b'' , 2b' , 2b

Specimen not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: Meckel's cartilage Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory