About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:199658 Moik D, et al., Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice. J Biol Chem. 2013 Jun 28;288(26):18863-71
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7433031
Gene symbol: Fn1
Gene name: fibronectin 1
Antibody: anti-Fibronectin (ab2033)
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 2C proximal control: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: basement membrane Present 2C upper left
TS13: blood island Present 2C upper left
Specimen 2C proximal ki/ki: embryonic day 8.5; Ilktm10.1Ref/Ilktm10.1Ref (more )
Structure Level Pattern Image Note
TS13: basement membrane Present 2C upper right
TS13: blood island Present 2C upper right
Specimen 2C distal control: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: basement membrane Present 2C lower left
TS13: yolk sac blood vessel Present 2C lower left
Specimen 2C distal ki/ki: embryonic day 8.5; Ilktm10.1Ref/Ilktm10.1Ref (more )
Structure Level Pattern Image Note
TS13: basement membrane Present 2C lower right
TS13: yolk sac blood vessel Absent 2C lower right Discernible distal vascular structures were not seen.
Specimen 2E control: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: basement membrane Present 2E FN left
TS13: neural ectoderm Present 2E FN left
Specimen 2E ki/ki: embryonic day 8.5; Ilktm10.1Ref/Ilktm10.1Ref (more )
Structure Level Pattern Image Note
TS13: basement membrane Present 2E FN right Normal basement membrane assembly as in the control.
TS13: neural ectoderm Present 2E FN right Normal basement membrane assembly as in the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory