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Gene Expression Data
Assay Details
Assay
Reference: J:332926 Zhou P, et al., Insm1 promotes differentiation of retinal progenitor cells toward photoreceptor cells in the developing retina through up-regulation of SHH. J Mol Histol. 2022 Dec;53(6):947-954
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7432968
Gene symbol: Insm1
Gene name: insulinoma-associated 1
Antibody: anti-Insm1 (sc-271408)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1a: embryonic day 12.5 (more )
Note: Double labeled: green - Insm1; red - Otx2 (assay MGI:7432969).
Structure Level Pattern Image Note
TS20: neural retina Strong Regionally restricted 1a Merge inset , 1a Insm1 inset , 1a Merge , 1a Insm1 Considerable expression, overlapping with Otx2 expression suggesting association with differentiation of photoreceptor precursor cells.
Specimen 1b: postnatal day 14 (more )
Note: Double labeled: green - Insm1; red - Rho (assay MGI:7432970).
Structure Level Pattern Image Note
TS28: retina outer nuclear layer Present Regionally restricted 1b Insm1 , 1b Merge , 1b Merge inset , 1b Insm1 inset Expression reduced in outer nuclear layer compared with level of expression at E12.5, overlapping with Rho expression.
Specimen 1c: postnatal day 14 (more )
Note: Double labeled: green - Insm1; red - Gfap (assay MGI:7432972).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Present Regionally restricted 1c Merge inset , 1c Insm1 , 1c Insm1 inset , 1c Merge Expression in inner nuclear layer, hardly overlapping with Gfap.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory