Bmpr2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:332879 Zheng J, et al., BMPR2 Variants Underlie Nonsyndromic Oligodontia. Int J Mol Sci. 2023 Jan 13;24(2)
Assay type:	RNA in situ
MGI Accession ID:	MGI:7432751
Gene symbol:	Bmpr2
Gene name:	bone morphogenetic protein receptor type 2

Probe:	Mm-Bmpr2 (493061)
Probe preparation:	Antisense
Visualized with:	Chromogenic
Assay notes:	Probe labeled using RNAscope 2.5 HD detection reagents-RED kit (Advanced Cell Diagnostics, 322360).

Results

4A ©

Specimen 4A: embryonic day 11.5 (more

)

Structure	Level	Pattern	Image	Note
TS19: dental placode	Present	Widespread	4A	Widely expressed in dental epithelium.
TS19: jaw primordium mesenchyme	Present	Regionally restricted	4A	Widely expressed in dental mesenchyme.

4B ©

Specimen 4B: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: dental placode	Present	Widespread	4B	Widely expressed in dental epithelium.
TS20: jaw primordium mesenchyme	Present	Regionally restricted	4B	Widely expressed in dental mesenchyme.

4C ©

Specimen 4C: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: tooth bud	Present	Widespread	4C	Widely expressed in dental epithelium.
TS21: lower jaw molar mesenchyme	Present	Regionally restricted	4C	Widely expressed in dental mesenchyme.

4D ©

Specimen 4D: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: cap stage tooth	Present	Widespread	4D	Widely expressed in dental epithelium and mesenchyme.
TS22: lower jaw molar dental follicle	Present		4D
TS22: lower jaw molar dental papilla	Present		4D
TS22: lower jaw molar enamel organ	Present		4D

4E ©

Specimen 4E: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: bell stage tooth	Present	Widespread	4E	Widely expressed in dental epithelium and mesenchyme.
TS23: lower jaw molar	Present	Widespread	4E	Widely expressed in dental epithelium and mesenchyme.
TS23: inner enamel epithelium	Strong		4E
TS23: lower jaw molar dental papilla	Strong		4E
TS23: outer enamel epithelium	Strong		4E
TS23: secondary enamel knot	Strong		4E
TS23: stellate reticulum	Weak		4E

4F ©

Specimen 4F: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: bell stage tooth	Present	Regionally restricted	4F	Widely expressed in dental epithelium and mesenchyme.
TS24: lower jaw molar	Present	Regionally restricted	4F	Widely expressed in dental epithelium and mesenchyme.
TS24: inner enamel epithelium	Strong	Regionally restricted	4F
TS24: lower jaw molar dental papilla	Strong	Regionally restricted	4F
TS24: outer enamel epithelium	Strong	Regionally restricted	4F
TS24: secondary enamel knot	Strong	Regionally restricted	4F
TS24: stellate reticulum	Weak	Regionally restricted	4F

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/18/2025 MGI 6.24