Gene Expression Data
Assay Details
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Assay
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Reference:
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J:332792
Horakova L, et al., Eda controls the size of the enamel knot during incisor development. Front Physiol. 2022;13:1033130
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7432647
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Gene symbol:
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Shh
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Gene name:
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sonic hedgehog
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Results
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Specimen
S2A:
embryonic day 12.5
(more  )
Specimen
S2A:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: mandible primordium |
Present |
Regionally restricted |
S2A
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Early superficial expression apparent anteriorly in initiation signalling center in both control and Eda-/- mandibles.
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Specimen
S2B:
embryonic day 12.5; EdaTa/ EdaTa
(more )
Specimen
S2B:
(close )
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Genetic Background:
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B6CBACa Aw-J/A-EdaTa/J-XO
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Mutant Allele(s):
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EdaTa/EdaTa
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: mandible primordium |
Present |
Regionally restricted |
S2B
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Early superficial expression apparent anteriorly in initiation signalling center in both control and Eda-/- mandibles.
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Specimen
2A:
embryonic day 13.5; EdaTa/ EdaTa
(more )
Specimen
2A:
(close )
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Genetic Background:
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B6CBACa Aw-J/A-EdaTa/J-XO
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Mutant Allele(s):
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EdaTa/EdaTa
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: lower jaw |
Present |
Regionally restricted |
2A
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Anterior expressing region split medio-laterally into two small areas.
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Specimen
2B:
embryonic day 13.5; EdaTa/ EdaTa
(more )
Specimen
2B:
(close )
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Genetic Background:
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B6CBACa Aw-J/A-EdaTa/J-XO
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Mutant Allele(s):
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EdaTa/EdaTa
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: lower jaw |
Present |
Regionally restricted |
2B
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Anterior expressing region split medio-laterally into two small areas.
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Specimen
2C:
embryonic day 14.5; EdaTa/ EdaTa
(more )
Specimen
2C:
(close )
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Genetic Background:
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B6CBACa Aw-J/A-EdaTa/J-XO
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Mutant Allele(s):
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EdaTa/EdaTa
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: enamel knot |
Weak |
Regionally restricted |
2C
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Posterior expression in enamel knot of incisor bud. Appearance of posterior expression substantially delayed and reduced in intensity compared to control.
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Specimen
2D:
embryonic day 13.5
(more )
Specimen
2D:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: lower jaw |
Present |
Regionally restricted |
2D
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Anterior expressing region split medio-laterally into two small areas.
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Specimen
2E:
embryonic day 13.5
(more )
Specimen
2E:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: lower jaw |
Present |
Regionally restricted |
2E
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Anterior expressing region split medio-laterally into two small areas.
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Specimen
2F:
embryonic day 14.5
(more )
Specimen
2F:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: lower jaw |
Present |
Regionally restricted |
2F
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Only one initiation expression region in anterior part of incisor area.
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Specimen
2G:
embryonic day 14.5
(more )
Specimen
2G:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: lower jaw |
Present |
Regionally restricted |
2G
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Co-existing anterior and posterior regions of expression.
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| TS22: enamel knot |
Present |
Regionally restricted |
2G
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Posterior expression in enamel knot of incisor bud.
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Specimen
2H:
embryonic day 15.5
(more )
Specimen
2H:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: enamel knot |
Present |
Regionally restricted |
2H
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Only posterior expression region remains visible.
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Analysis Tools