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Gene Expression Data
Assay Details
Assay
Reference: J:80873 Asou Y, et al., Coordinated expression of scleraxis and Sox9 genes during embryonic development of tendons and cartilage. J Orthop Res. 2002 Jul;20(4):827-33
Assay type: RNA in situ
MGI Accession ID: MGI:7432499
Gene symbol: Scx
Gene name: scleraxis scleraxis bHLH transcription factor
Probe: Scleraxis cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1a: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: sclerotome Present 1a

Specimen 1b: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: sclerotome Present Regionally restricted 1b , 1c Expression is in the lateral part.

Specimen 2a: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: rib pre-cartilage condensation Present Regionally restricted 2a Expression is in the ventral and dorsal surface.

Specimen 2c: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: intercostal muscle Present Regionally restricted 2c Expression is at the interface of the intercostal muscles and the surface of the rib primordia.
TS21: rib cartilage condensation Present Regionally restricted 2c Expression is at the interface of the intercostal muscles and the surface of the rib primordia.

Specimen 3a: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: limb Present Regionally restricted 3a Expression is in the medio-ventral and medio-dorsal part and is absent in the center.

Specimen 3b: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: limb mesenchyme Present Regionally restricted 3b Expression is surrounding the skeletal primordia.

Specimen 4a: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: limb Present Regionally restricted 4a Expression is along the proximo-distal axis starting from the muscle/tendon boundary towards the distal end of each digit.
TS20: limb digit Present Regionally restricted 4a Expression is along the proximo-distal axis starting from the muscle/tendon boundary towards the distal end of each digit.
TS20: limb musculature Present Regionally restricted 4a Expression is along the proximo-distal axis starting from the muscle/tendon boundary towards the distal end of each digit.
TS20: limb tendon primordium Present Regionally restricted 4a Expression is along the proximo-distal axis starting from the muscle/tendon boundary towards the distal end of each digit.

Specimen 4b: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: embryo Present Regionally restricted 4b Expression is in tissues attached to the ends of the appendicular skeleton.
TS20: skeleton Present Regionally restricted 4b Expression is in tissues attached to the ends of the appendicular skeleton.
TS20: tendon Present 4b

Specimen 5a: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: phalanx pre-cartilage condensation Present Regionally restricted 5a Expression is either ventral or dorsal in the distal and proximal part of each phalanx in regions where the putative flexor and extensor tendons are developing.

Specimen 5b: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: phalanx pre-cartilage condensation Present Regionally restricted 5b Expression is either ventral or dorsal in the distal and proximal part of each phalanx.

Specimen 6a: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: hindlimb phalanx Present Regionally restricted 6a Expression is in tendons of the phalanges.
TS23: hindlimb tendon primordium Present Regionally restricted 6a Expression is in tendons of the phalanges.

Specimen 6b: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: shoulder joint primordium Present Regionally restricted 6b Expression is in the primordia of the rotator cuff.

Specimen 6c: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: knee joint Present Regionally restricted 6c Expression is in the collateral ligaments.
TS24: cruciate ligament of knee Present Regionally restricted 6c Expression is in the anterior cruciate ligament.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory