Gene Expression Data
Assay Details
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Assay
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Reference:
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J:75868
Lu QR, et al., Common developmental requirement for olig function indicates a motor neuron/oligodendrocyte connection. Cell. 2002 Apr 5;109(1):75-86
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7432426
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Gene symbol:
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Olig1
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Gene name:
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oligodendrocyte transcription factor 1
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Results
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Specimen
1C +/-:
(close  )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Olig1tm1(cre)Rth/Olig1+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
1C -/-:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Olig1tm1(cre)Rth/Olig1tm1(cre)Rth
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
3C +/+:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Olig1tm1(cre)Rth/Olig1tm1(cre)Rth
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
3C -/-:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Olig2tm1Rth/Olig2tm1Rth
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: hindbrain |
Present |
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3C-3
,
3C-4
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Expressed in the hindbrain at positions where oligodendrocyte precursors were observed in Olig2 null mice.
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Specimen
6 +/+ E9.5:
embryonic day 9.5
(more  )
Specimen
6 +/+ E9.5:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
6 -/- E9.5:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Olig2tm1Rth/Olig2tm1Rth
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: neural tube lateral wall |
Present |
Regionally restricted |
6_-/- 9.5
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More robust expression in the ventral neural tube, compared with the wild-type.
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Specimen
6 +/+ E11.5:
embryonic day 11.5
(more )
Specimen
6 +/+ E11.5:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: neural tube lateral wall |
Ambiguous |
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6_+/+ 11.5
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Reduced expression in the ventral neural tube, compared with that of E9.5.
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Specimen
6 -/- E11.5:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Olig2tm1Rth/Olig2tm1Rth
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: neural tube lateral wall |
Present |
Regionally restricted |
6_-/- 11.5
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More robust expression in the ventral neural tube, compared with the wild-type.
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Specimen
6 +/+ E12.5:
embryonic day 12.5
(more )
Specimen
6 +/+ E12.5:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
6 -/- E12.5:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Olig2tm1Rth/Olig2tm1Rth
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: spinal cord lateral wall |
Present |
Regionally restricted |
6_-/- 12.5
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More robust expression in the ventral neural tube, compared with the wild-type.
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Specimen
6 +/+ E13.5:
embryonic day 13.5
(more )
Specimen
6 +/+ E13.5:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: spinal cord lateral wall |
Present |
Regionally restricted |
6_+/+ 13.5
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Positive cells migrated outwards from the ventral neural tube.
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Specimen
6 -/- E13.5:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Olig2tm1Rth/Olig2tm1Rth
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: spinal cord lateral wall |
Present |
Regionally restricted |
6_-/- 13.5
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Reduced migration and/or proliferation of positive cells compared with the wild-type.
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Specimen
6 +/+ E14.5:
embryonic day 14.5
(more )
Specimen
6 +/+ E14.5:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
6 -/- E14.5:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Olig2tm1Rth/Olig2tm1Rth
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: spinal cord lateral wall |
Present |
Regionally restricted |
6_-/- 14.5
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Reduced migration and/or proliferation of positive cells compared with the wild-type.
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Specimen
6 +/+ E18.5:
embryonic day 18.5
(more )
Specimen
6 +/+ E18.5:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
6 -/- E18.5:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Olig2tm1Rth/Olig2tm1Rth
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: spinal cord lateral wall |
Present |
Regionally restricted |
6_-/- 18.5
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Reduced migration and/or proliferation of positive cells compared with the wild-type.
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Specimen
6 -/- E12.5 neo:
embryonic day 12.5; Olig2tm1Rth/ Olig2tm1Rth
(more )
Note: Double labeled: purple - Olig1; brown - Olig2-neo.
Specimen
6 -/- E12.5 neo:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6J
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Mutant Allele(s):
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Olig2tm1Rth/Olig2tm1Rth
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Double labeled: purple - Olig1; brown - Olig2-neo.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: spinal cord lateral wall |
Present |
Regionally restricted |
6_neo/Olig1 12.5
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Colocalization of Olig1 and Olig2-neo was seen in the ventral region.
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