About   Help   FAQ
Cd6em1(cre/ERT2)Maik
Endonuclease-mediated Allele Detail
Summary
Symbol: Cd6em1(cre/ERT2)Maik
Name: CD6 antigen; endonuclease-mediated mutation 1, Masahito Ikawa
MGI ID: MGI:7431261
Gene: Cd6  Location: Chr19:10766705-10807422 bp, - strand  Genetic Position: Chr19, 7.16 cM
Alliance: Cd6em1(cre/ERT2)Maik page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:332932
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Conditional ready, Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Cd6em1(cre/ERT2)Maik expression driven by 1 gene
 
Mutation detailsA CAG-CreERT2-EF1-copGFP2aPuro cassette was inserted via CRISPR/cas9 endonuclease-mediated genome editing in the ES cells. (J:332932)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cd6 (mouse)
Summary of all recombinase alleles driven by Cd6.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd6 Mutation:  27 strains or lines available
Notes
Lentiviral gene trap injected into zygotes.
References
Original:  J:332932 Ozawa M, et al., Efficient simultaneous double DNA knock-in in murine embryonic stem cells by CRISPR/Cas9 ribonucleoprotein-mediated circular plasmid targeting for generating gene-manipulated mice. Sci Rep. 2022 Dec 13;12(1):21558
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/23/2024
MGI 6.23
The Jackson Laboratory