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Tg(tetO-Pum2)1Jtm
Transgene Detail
Summary
Symbol: Tg(tetO-Pum2)1Jtm
Name: transgene insertion 1, Joshua Mendell
MGI ID: MGI:7431250
Synonyms: TRE-FLAG-Pum2
Transgene: Tg(tetO-Pum2)1Jtm  Location: unknown  Genetic Position: ChrUN, Syntenic
Alliance: Tg(tetO-Pum2)1Jtm page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(tetO-Pum2)1Jtm expresses 1 gene
 
Mutation detailsA FLAG-tagged mouse Pum2 coding sequence (isoform 3; GenBank BC041773) and a synthetic intron were cloned into the pTRE-Tight vector to enable conditional expression of the transgene from the tight TRE (tetracycline response element; tetO) promoter. (J:275996)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:275996 Kopp F, et al., PUMILIO hyperactivity drives premature aging of Norad-deficient mice. Elife. 2019 Feb 8;8:e42650
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory