About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:195652 Manso AM, et al., Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload. J Biol Chem. 2013 Feb 8;288(6):4252-64
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7431107
Gene symbol: Vcl
Gene name: vinculin
Antibody: anti-Vinculin (V9131) clone hVIN-1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen S7 Control (upper): postnatal adult (more )
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Present S7_Control Vcl (upper) , S7_Control Vcl+Cre (upper) Similar expression intensity and localization in control and mutant tissue.
Specimen S7 Control (lower): postnatal adult (more )
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Present S7_Control Vcl+Cre (lower) , S7_Control Vcl (lower) Similar expression intensity and localization in control and mutant tissue.
Specimen S7 Tln1cKO (upper): postnatal adult; Tg(Myhca-cre)1Abel/0, Tln1tm4.1Crit/Tln1tm4.1Crit (more )
Note: Conditional mutant. Double labeled: green - Vcl; red - Cre
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Present S7_Tln1cKO Vcl (upper) , S7_Tln1cKO Vcl+Cre (upper) Similar expression intensity and localization in control and mutant tissue.
Specimen S7 Tln1cKO (lower): postnatal adult; Tg(Myhca-cre)1Abel/0, Tln1tm4.1Crit/Tln1tm4.1Crit (more )
Note: Conditional mutant. Double labeled: green - Vcl; red - Cre
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Present S7_Tln1cKO Vcl (lower) , S7_Tln1cKO Vcl+Cre (lower) Similar expression intensity and localization in control and mutant tissue.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory