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Gene Expression Data
Assay Details
Assay
Reference: J:195652 Manso AM, et al., Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload. J Biol Chem. 2013 Feb 8;288(6):4252-64
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7431107
Gene symbol: Vcl
Gene name: vinculin
Antibody: anti-Vinculin (V9131) clone hVIN-1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen S7 Control (upper): postnatal adult (more )
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Present S7_Control Vcl (upper) , S7_Control Vcl+Cre (upper) Similar expression intensity and localization in control and mutant tissue.
Specimen S7 Control (lower): postnatal adult (more )
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Present S7_Control Vcl+Cre (lower) , S7_Control Vcl (lower) Similar expression intensity and localization in control and mutant tissue.
Specimen S7 Tln1cKO (upper): postnatal adult; Tg(Myhca-cre)1Abel/0, Tln1tm4.1Crit/Tln1tm4.1Crit (more )
Note: Conditional mutant. Double labeled: green - Vcl; red - Cre
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Present S7_Tln1cKO Vcl (upper) , S7_Tln1cKO Vcl+Cre (upper) Similar expression intensity and localization in control and mutant tissue.
Specimen S7 Tln1cKO (lower): postnatal adult; Tg(Myhca-cre)1Abel/0, Tln1tm4.1Crit/Tln1tm4.1Crit (more )
Note: Conditional mutant. Double labeled: green - Vcl; red - Cre
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Present S7_Tln1cKO Vcl (lower) , S7_Tln1cKO Vcl+Cre (lower) Similar expression intensity and localization in control and mutant tissue.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory