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Gene Expression Data
Assay Details
Assay
Reference: J:195652 Manso AM, et al., Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload. J Biol Chem. 2013 Feb 8;288(6):4252-64
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7431101
Gene symbol: Tln1
Gene name: talin 1
Antibody: anti-Talin-1 (97H6)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1B Tln1: embryonic day 9.0 (more )
Note: Double labeled: green - Tln1; red - Ttn (assay MGI:7431103).
Structure Cell Type Level Pattern Image Note
TS14: cardiac muscle tissue cardiac muscle cell Present 1B Tln1+Titin , 1B Tln1+Titin (inset) , 1B Tln1 Expression in cardiomyocytes, co-localized with Ttn expression.
Specimen 1C Tln1: embryonic day 10.0 (more )
Note: Double labeled: green - Tln1; red - Pecam1 (assay MGI:7431104).
Structure Cell Type Level Pattern Image Note
TS16: heart cardiac endothelial cell Present 1C Tln1 , 1C Tln1+PECAM
Specimen 2Ab,c: postnatal adult (more )
Note: Double labeled: green - Tln1; red - Dys (Dmd assay MGI:7431105).
Structure Cell Type Level Pattern Image Note
TS28: cardiac muscle tissue cardiac muscle cell Trace Regionally restricted 2Ab , 2Ac Minimal expression in cardiomyocytes. Expression not detected in cardiomyocyte membrane.
Specimen 2Ae,f: postnatal adult (more )
Note: Double labeled: green - Tln1; red - Pecam1 (assay MGI:7431104).
Structure Cell Type Level Pattern Image Note
TS28: heart cardiac endothelial cell Present 2Af , 2Ae Expression only in endothelial cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory