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Gene Expression Data
Assay Details
Assay
Reference: J:260151 Ito K, et al., Lack of Fgf18 causes abnormal clustering of motor nerve terminals at the neuromuscular junction with reduced acetylcholine receptor clusters. Sci Rep. 2018 Jan 11;8(1):434
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7427794
Gene symbol: Fgf18
Gene name: fibroblast growth factor 18
Antibody: anti-Fgf18 (sc-16830)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2A,B,D: postnatal adult (more )
Note: Double labeled: green - Fgf18; red - Chat (assay MGI:7427795).
Structure Cell Type Level Pattern Image Note
TS28: spinal cord spinal cord motor neuron Present 2B , 2D , 2A Expression co-localized with that of Chat in spinal motor neurons.
Specimen 2E Adult Fgf18+/+: postnatal adult (more )
Note: Double labeled: green - Fgf18; red - AChR.
Structure Level Pattern Image Note
TS28: tibialis anterior Present Regionally restricted 2E Adult Fgf18+/+ (merge) , 2E Adult Fgf18+/+ FGF18 Expression co-localizes with AChR clusters.
Specimen 2E E18.5 Fgf18+/+: embryonic day 18.5 (more )
Note: Double labeled: green - Fgf18; red - AChR.
Structure Level Pattern Image Note
TS26: upper leg muscle Present Regionally restricted 2E E18.5 Fgf18+/+ FGF18 , 2E E18.5 Fgf18+/+ (merge) Expression co-localizes with AChR clusters.
Specimen 2E E18.5 Fgf18-/-: embryonic day 18.5; Fgf18tm1Sjt/Fgf18tm1Sjt (more )
Note: Double labeled: green - Fgf18; red - AChR.
Structure Level Pattern Image Note
TS26: upper leg muscle Present Regionally restricted 2E E18.5 Fgf18-/- (merge) , 2E E18.5 Fgf18-/- FGF18 Expression co-localizes with AChR clusters.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory