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Gene Expression Data
Assay Details
Assay
Reference: J:253585 Siletti K, et al., Daple coordinates organ-wide and cell-intrinsic polarity to pattern inner-ear hair bundles. Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11170-E11179
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7427540
Gene symbol: Vangl2
Gene name: VANGL planar cell polarity 2
Antibody: anti-pan-Vangl (ABN373)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: Fixation was with TCA.
Results
Specimen 7A Daple+/-: postnatal day 2; Ccdc88ctm1(KOMP)Mbp/Ccdc88c+ (more )
Note: Triple labeled: green - Vangl2; magenta - Fzd6 (assay MGI:7427541); gray - phalloidin.
Structure Level Pattern Image Note
TS27: cochlea Present Regionally restricted 7A Vangl-2 Daple+/- , 7A Merged Daple+/- Expression at neural junctions between hair cells and supporting cells.
Specimen 7A Daple-/-: postnatal day 2; Ccdc88ctm1(KOMP)Mbp/Ccdc88ctm1(KOMP)Mbp (more )
Note: Triple labeled: green - Vangl2; magenta - Fzd6 (assay MGI:7427541); gray - phalloidin.
Structure Level Pattern Image Note
TS27: cochlea Present Regionally restricted 7A Merged Daple-/- , 7A Vangl-2 Daple-/- Expression at neural junctions between hair cells and supporting cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
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