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Gene Expression Data
Assay Details
Assay
Reference: J:253585 Siletti K, et al., Daple coordinates organ-wide and cell-intrinsic polarity to pattern inner-ear hair bundles. Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11170-E11179
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7427537
Gene symbol: Pcnt
Gene name: pericentrin (kendrin)
Antibody: Anti-Pericentrin
Detection system: Secondary antibody
Results
Specimen 5B Daple+/-: embryonic day 17.5; Ccdc88ctm1(KOMP)Mbp/Ccdc88c+ (more )
Note: Double labeled: red - Pcnt; blue - Phalloidin.
Structure Cell Type Level Pattern Image Note
TS25: cochlea cochlea auditory hair cell Present Regionally restricted 5B Daple+/- Expression in hair cells at cochlear apex. Kinocilia primarily at center of hair cells.
Specimen 5B Daple-/-: embryonic day 17.5; Ccdc88ctm1(KOMP)Mbp/Ccdc88ctm1(KOMP)Mbp (more )
Note: Double labeled: red - Pcnt; blue - Phalloidin.
Structure Cell Type Level Pattern Image Note
TS25: cochlea cochlea auditory hair cell Present Regionally restricted 5B Daple-/- Expression in hair cells at cochlear apex. Kinocilia primarily at center of hair cells.
Specimen 5C Daple+/-: embryonic day 17.5; Ccdc88ctm1(KOMP)Mbp/Ccdc88c+ (more )
Note: Double labeled: red - Pcnt; blue - Phalloidin.
Structure Cell Type Level Pattern Image Note
TS25: cochlea cochlea auditory hair cell Present Regionally restricted 5C Daple+/- Expression in hair cells at middle turn of cochlea. Kinocilia prmarily at abneural edges of hair cells.
Specimen 5C Daple-/-: embryonic day 17.5; Ccdc88ctm1(KOMP)Mbp/Ccdc88ctm1(KOMP)Mbp (more )
Note: Double labeled: red - Pcnt; blue - Phalloidin.
Structure Cell Type Level Pattern Image Note
TS25: cochlea cochlea auditory hair cell Present Regionally restricted 5C Daple-/- Expression in hair cells at middle turn of cochlea. Many kinocilia at neural edges of hair cells.
Specimen 5D Daple+/-: embryonic day 17.5; Ccdc88ctm1(KOMP)Mbp/Ccdc88c+ (more )
Note: Double labeled: red - Pcnt; blue - Phalloidin.
Structure Cell Type Level Pattern Image Note
TS25: cochlea cochlea auditory hair cell Present Regionally restricted 5D Daple+/- Expression in basal hair cells. Kinocilia primarily at aneural edges of hair cells.
Specimen 5D Daple-/-: embryonic day 17.5; Ccdc88ctm1(KOMP)Mbp/Ccdc88ctm1(KOMP)Mbp (more )
Note: Double labeled: red - Pcnt; blue - Phalloidin.
Structure Cell Type Level Pattern Image Note
TS25: cochlea cochlea auditory hair cell Present Regionally restricted 5D Daple-/- Expression in basal hair cells. Many kinocilia at neural edges of hair cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory