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Gene Expression Data
Assay Details
Assay
Reference: J:235650 Mao H, et al., Haploinsufficiency for Core Exon Junction Complex Components Disrupts Embryonic Neurogenesis and Causes p53-Mediated Microcephaly. PLoS Genet. 2016 Sep;12(9):e1006282
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7425188
Gene symbol: Tbr1
Gene name: T-box brain transcription factor 1
Antibody: anti-Tbr1
Detection system: Secondary antibody
Results
Specimen 10I: embryonic day 18.5; Emx1tm1(cre)Krj/Emx1+ (more )
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex cerebral cortex neuron Present Regionally restricted 10I Expression in deep layer neurons.
Specimen 10J: embryonic day 18.5; Emx1tm1(cre)Krj/Emx1+, Rbm8atm1Dlsi/Rbm8a+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: cerebral cortex Present Regionally restricted 10J Normal number of expressing cells, but distribution is skewed basally.
Specimen 10K: embryonic day 18.5; Emx1tm1(cre)Krj/Emx1+, Trp53tm1Brn/Trp53tm1Brn (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: cerebral cortex Present 10K
Specimen 10L: embryonic day 18.5; Emx1tm1(cre)Krj/Emx1+, Rbm8atm1Dlsi/Rbm8a+, Trp53tm1Brn/Trp53tm1Brn (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex cerebral cortex neuron Present Regionally restricted 10L Neuron disribution is restored to normal.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory