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Gene Expression Data
Assay Details
Assay
Reference: J:235650 Mao H, et al., Haploinsufficiency for Core Exon Junction Complex Components Disrupts Embryonic Neurogenesis and Causes p53-Mediated Microcephaly. PLoS Genet. 2016 Sep;12(9):e1006282
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7425187
Gene symbol: Satb2
Gene name: special AT-rich sequence binding protein 2
Antibody: anti-Satb2
Detection system: Secondary antibody
Results
Specimen S7E: embryonic day 18.5; Emx1tm1(cre)Krj/Emx1+ (more )
Structure Cell Type Level Pattern Image Note
TS26: cerebral cortex neuron Present Regionally restricted S7E Expression in both superficial and some deep layer neurons.
Specimen S7F: embryonic day 18.5; Emx1tm1(cre)Krj/Emx1+, Rbm8atm1Dlsi/Rbm8a+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: cerebral cortex Weak S7F Expression reduced compared to control.
Specimen S7G: embryonic day 18.5; Emx1tm1(cre)Krj/Emx1+, Trp53tm1Brn/Trp53tm1Brn (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: cerebral cortex Present S7G
Specimen S7H: embryonic day 18.5; Emx1tm1(cre)Krj/Emx1+, Rbm8atm1Dlsi/Rbm8a+, Trp53tm1Brn/Trp53tm1Brn (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: cerebral cortex Present S7H Expression partially rescued in p53 null background.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory