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Gene Expression Data
Assay Details
Assay
Reference: J:332131 Perera SN, et al., Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584
Assay type: RNA in situ
MGI Accession ID: MGI:7425004
Gene symbol: Hes1
Gene name: hes family bHLH transcription factor 1
Probe: Hes1 cDNA12
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 7 - Hes1: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Absent 7o , 7n The ONL-OECs lack expression.
TS24: olfactory nerve olfactory ensheathing cell Present 7n , 7p At least some mucosal OECs show expression.
TS24: trigeminal nerve Schwann cell Present Single cells 7n , 7q A few Schwann cells show expression.
TS24: head mesenchyme Present Regionally restricted 7q , 7n , 7o , 7p Expression is seen in mesenchyme surrounding the ONL as well as by mesenchyme near both olfactory and trigeminal nerve fascicles.
Specimen 11 - E11.5: embryonic day 11.5 (more )
Note: Parasagittal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS20: olfactory nerve olfactory ensheathing cell Present Regionally restricted 11b , 11c Some mucosal OECs show expression.
Specimen 11 - E13.5: embryonic day 13.5 (more )
Note: Parasagittal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS22: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Absent 11e , 11d The ONL-OECs lack expression.
TS22: olfactory nerve olfactory ensheathing cell Present Regionally restricted 11f , 11d Some mucosal OECs show expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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