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Gene Expression Data
Assay Details
Assay
Reference: J:332131 Perera SN, et al., Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584
Assay type: RNA in situ
MGI Accession ID: MGI:7425002
Gene symbol: Hes5
Gene name: hes family bHLH transcription factor 5
Probe: Hes5 cDNA11
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 7 - Hes5: embryonic day 15.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS23: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Present Non-Uniform 7j , 7k The inner ONL-OECs show stronger expression than the outer ones.
TS23: olfactory nerve olfactory ensheathing cell Absent 7j , 7l The mucosal OECs lack expression.
TS23: trigeminal nerve Schwann cell Absent 7m , 7j The Schwann cells lack expression.
Specimen 10 - E11.5: embryonic day 11.5 (more )
Note: Parasagittal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS20: olfactory nerve olfactory ensheathing cell Absent 10b , 10c The mucosal OECs lack expression.
Specimen 10 - E13.5: embryonic day 13.5 (more )
Note: Parasagittal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS22: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Present Regionally restricted 10e , 10d Expression is restricted to the ONL-OECs within three cell diameters of the olfactory bulb.
TS22: olfactory nerve olfactory ensheathing cell Absent 10d , 10f The mucosal OECs lack expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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