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Gene Expression Data
Assay Details
Assay
Reference: J:332131 Perera SN, et al., Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584
Assay type: RNA in situ
MGI Accession ID: MGI:7424975
Gene symbol: Dpysl3
Gene name: dihydropyrimidinase-like 3
Probe: Crmp4 cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 5 - Dpysl3: embryonic day 16.5 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS24: main olfactory bulb olfactory nerve layer olfactory ensheathing cell Present Non-Uniform 5g , 5f The inner ONL-OECs show stronger expression than the outer ones.
TS24: olfactory nerve olfactory ensheathing cell Present 5f , 5h The mucosal OECs show expression.
TS24: trigeminal nerve Schwann cell Absent 5i , 5f The Schwann cells lack expression.
TS24: main olfactory bulb Very strong 5g , 5f
TS24: olfactory epithelium Very strong 5f , 5h
TS24: olfactory nerve Very strong Scattered 5h , 5f Very strongly expressing cells are seen on the olfactory nerve; it is assumed they are migrating neurons.
Specimen S7 - E11.5: embryonic day 11.5 (more )
Note: Parasagittal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS20: olfactory nerve olfactory ensheathing cell Weak S7G , S7H The mucosal OECs show weak expression.
TS20: olfactory epithelium Strong S7G , S7H
TS20: forebrain Strong Regionally restricted S7H , S7G Strong expression is seen at the edge of the rostral forebrain.
TS20: olfactory nerve Strong Single cells S7G , S7H Strongly expressing cells are seen on the olfactory nerve; it is assumed they are migrating neurons.
Specimen S7 - E13 - I1: embryonic day 13.0 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS21: main olfactory bulb layer olfactory ensheathing cell Present S7I1 , S7J1 The olfactory nerve layer OECs show expression.
TS21: main olfactory bulb Strong S7I1 , S7J1
Specimen S7 - E13 - I2: embryonic day 13.0 (more )
Note: Coronal section. Immunostained with Sox10 (green) to label olfactory entheathing cells (OECs) and Schwann cells and Tubb3 (magenta) to identify axons.
Structure Cell Type Level Pattern Image Note
TS21: olfactory nerve olfactory ensheathing cell Present S7I2 , S7J2 The mucosal OECs show expression.
TS21: olfactory nerve Strong Single cells S7J2 , S7I2 Strongly expressing cells are seen on the olfactory nerve; it is assumed they are migrating neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory