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Tg(Gata3-lacZ)-2052Jeng
Transgene Detail
Summary
Symbol: Tg(Gata3-lacZ)-2052Jeng
Name: transgene insertion -2052, James Douglas Engel
MGI ID: MGI:7413954
Synonyms: -2052placZ
Transgene: Tg(Gata3-lacZ)-2052Jeng  Location: unknown  
Alliance: Tg(Gata3-lacZ)-2052Jeng page
Transgene
origin
Strain of Origin:  CD-1
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsFor the transgene insert, genomic sequence from approximately -2052 bp (relative to Gata3 transcription start site in CD-1 strain) to the 5' end of intron 2 (which includes upstream regulatory sequences, exon 1b, intron 1b, exon 2 and part of intron 2) was modified by the insertion of a beta-galactosidase reporter gene cassette (which includes poly(A) signal sequence) in place of the Gata3 ATG start site. The reporter is expressed in embryo limb bud muscle, intercostal muscle and cranial ganglia. (J:332297)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:332297 Lieuw KH, et al., Temporal and spatial control of murine GATA-3 transcription by promoter-proximal regulatory elements. Dev Biol. 1997 Aug 1;188(1):1-16
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory