Tg(RP23-43G17)delta7.1Jeng
Transgene Detail
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| Symbol: |
Tg(RP23-43G17)delta7.1Jeng |
| Name: |
transgene insertion delta7.1, James Douglas Engel |
| MGI ID: |
MGI:7413116 |
| Synonyms: |
Tg43G17delta7.1 |
| Transgene: |
Tg(RP23-43G17)delta7.1Jeng Location: unknown
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| Alliance: |
Tg(RP23-43G17)delta7.1Jeng page
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| Transgene Type: |
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Transgenic (Reporter) |
| Mutation: |
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Insertion
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Mutation details: The transgene insert contains the following elements: an FRT site flanked neomycin resistance gene cassette, Gata3 promoter 1b (-1314 to +1 relative to ATG start site; contains downstream promoter, alternative 1st exon 1b, intron 1b and 5' UTR part of exon 2), the EGFP reporter gene cDNA, and BAC RP23-43G17 (which contains Gata3 T cell and thymic NK cell enhancer (7.1 kb KpnI-SalI T cell element) Rr338) where Rr338 was replaced with an FRT site flanked neomycin resistance gene cassette. The neo cassettes were removed through subsequent flp-mediated recombination. EGFP expression is not observed in thymocytes anymore.
(J:281897)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:281897 Hosoya-Ohmura S, et al., An NK and T cell enhancer lies 280 kilobase pairs 3' to the gata3 structural gene. Mol Cell Biol. 2011 May;31(9):1894-904 |
| All: |
1 reference(s) |
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Analysis Tools
