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Tg(Gata3-lacZ)B124Jeng
Transgene Detail
Summary
Symbol: Tg(Gata3-lacZ)B124Jeng
Name: transgene insertion B124, James Douglas Engel
MGI ID: MGI:7413196
Synonyms: B124lacZ
Transgene: Tg(Gata3-lacZ)B124Jeng  Location: unknown  
Alliance: Tg(Gata3-lacZ)B124Jeng page
Transgene
origin
Strain of Origin:  Not Applicable
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe transgene contains a ~540 kb B1 repeat deletion subfragment of ~825 kb C57BL/6 YAC ICRFy902H125. The YAC contains the entire Gata3 gene plus upstream and downstream regulatory regions and was modified by inserting a lacZ beta-galactosidase reporter gene cassette immediately downstream of (in-frame with) the Gata3 ATG start site. The reporter gene is expressed in many but not all tissues that normally express Gata3 during embryonic development. (J:52950)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:51930 Lakshmanan G, et al., Partial rescue of GATA-3 by yeast artificial chromosome transgenes. Dev Biol. 1998 Dec 15;204(2):451-63
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory