Tg(Gata3)C4Jeng
Transgene Detail
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Symbol: |
Tg(Gata3)C4Jeng |
Name: |
transgene insertion C4, James Douglas Engel |
MGI ID: |
MGI:7413192 |
Synonyms: |
C4loxP |
Transgene: |
Tg(Gata3)C4Jeng Location: unknown
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Alliance: |
Tg(Gata3)C4Jeng page
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Strain of Origin: |
Not Applicable
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Transgene Type: |
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Transgenic (Conditional ready, Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Gata3)C4Jeng expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Gata3 (MGI:95663) |
Exon 2 floxed |
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Mutation details: The transgene contains a ~120 kb B1 repeat deletion subfragment of ~485 kb C3H YAC ICRFy903F1113. The YAC contains the entire Gata3 gene plus upstream and downstream regulatory regions and was modified by inserting loxP sites into introns 1 and 2. Diagnostic SacII and XhoI were engineered in introns 1 and 2, respectively. Three mouse lines were established.
(J:51930)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:51930 Lakshmanan G, et al., Partial rescue of GATA-3 by yeast artificial chromosome transgenes. Dev Biol. 1998 Dec 15;204(2):451-63 |
All: |
1 reference(s) |
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