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Gene Expression Data
Assay Details
Assay
Reference: J:235128 Katayama Y, et al., CHD8 haploinsufficiency results in autistic-like phenotypes in mice. Nature. 2016 Sep 29;537(7622):675-679
Assay type: Western blot
MGI Accession ID: MGI:7413083
Gene symbol: Chd8
Gene name: chromodomain helicase DNA binding protein 8
Antibody: anti-pan-CHD8
Results Image: ED2e
 Sample Information Bands Other Sample Information
Lane AgeStructure 280 kDa (a) Genetic BackgroundMutant Allele(s)Sex
Heart +/+ P w 9 TS28: heart Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
Heart +/deltaSL P w 9 TS28: heart Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
Heart +/+ P w 9 TS28: heart Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
Heart +/deltaL P w 9 TS28: heart Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
Thymus +/+ P w 9 TS28: thymus Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
Thymus +/deltaSL P w 9 TS28: thymus Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
Thymus +/+ P w 9 TS28: thymus Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
Thymus +/deltaL P w 9 TS28: thymus Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
Spleen +/+ P w 9 TS28: spleen Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
Spleen +/deltaSL P w 9 TS28: spleen Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Not Specified
Spleen +/+ P w 9 TS28: spleen Present involves: 129P2/OlaHsd * C57BL/6J Not Specified
Spleen +/deltaL P w 9 TS28: spleen Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Not Specified
Testis +/+ P w 9 TS28: testis Present involves: 129P2/OlaHsd * C57BL/6J Male
Testis +/deltaSL P w 9 TS28: testis Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm1Kei/Chd8+Male
Testis +/+ P w 9 TS28: testis Present involves: 129P2/OlaHsd * C57BL/6J Male
Testis +/deltaL P w 9 TS28: testis Weak (b) involves: 129P2/OlaHsd * C57BL/6J Chd8tm2.1Kei/Chd8+Male
Notes:
(a) CHD8L
(b) Level of expression was ~50% that of wild-type
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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