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Gene Expression Data
Assay Details
Assay
Reference: J:144146 Roebroek AJ, et al., Mutant Lrp1 knock-in mice generated by recombinase-mediated cassette exchange reveal differential importance of the NPXY motifs in the intracellular domain of LRP1 for normal fetal development. Mol Cell Biol. 2006 Jan;26(2):605-16
Assay type: Western blot
MGI Accession ID: MGI:7411156
Gene symbol: Lrp1
Gene name: low density lipoprotein receptor-related protein 1
Antibody: anti-LRP1
Assay notes: 4 to 12% NuPage gel
Results Image: 2H
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Genetic BackgroundMutant Allele(s)Sex
LRP1-WT liver P adult TS28: liver Present involves: 129P2/OlaHsd Not Specified
LRP1-furin-mut liver P adult TS28: liver Present (b) involves: 129P2/OlaHsd * C57BL/6 Lrp1tm2Ajmr/Lrp1tm2AjmrNot Specified
LRP-NPXY2-mut liver P adult TS28: liver Present (c) involves: 129P2/OlaHsd * C57BL/6 Lrp1tm4Ajmr/Lrp1tm4AjmrNot Specified
LRP1-WT brain P adult TS28: brain Present involves: 129P2/OlaHsd Not Specified
LRP1-furin-mut brain P adult TS28: brain Present (b) involves: 129P2/OlaHsd * C57BL/6 Lrp1tm2Ajmr/Lrp1tm2AjmrNot Specified
LRP-NPXY2-mut brain P adult TS28: brain Present (c) involves: 129P2/OlaHsd * C57BL/6 Lrp1tm4Ajmr/Lrp1tm4AjmrNot Specified
Notes:
(a) alpha subunit
(b) Clear impairment of maturation of pro-LRP1 into subunits.
(c) No difference in expression compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
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