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Myh1em1Tnsh
Endonuclease-mediated Allele Detail
Summary
Symbol: Myh1em1Tnsh
Name: myosin, heavy polypeptide 1, skeletal muscle, adult; endonuclease-mediated mutation 1, Takanori Nishimura
MGI ID: MGI:7411129
Synonyms: KuO-Myh1
Gene: Myh1  Location: Chr11:67090922-67115401 bp, + strand  Genetic Position: Chr11, 40.59 cM
Alliance: Myh1em1Tnsh page
Mutation
origin
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Endonuclease-mediated (Reporter)
Mutation:    Insertion
 
Mutation detailsCRISPR-targeting inserted the Kusabira Orange fluorescence protein (KuO) reporter gene at the start codon in exon 3. (J:330862)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Myh1 Mutation:  109 strains or lines available
References
Original:  J:330862 Ojima K, et al., Endogenous slow and fast myosin dynamics in myofibers isolated from mice expressing GFP-Myh7 and Kusabira Orange-Myh1. Am J Physiol Cell Physiol. 2022 Aug 1;323(2):C520-C535
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory