Prkdc Western blot Gene Expression Assay - GXD

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Gene Expression Data
Assay Details

Assay

Reference:	J:331871 Rodriguez A, et al., TGFbeta pathway is required for viable gestation of Fanconi anemia embryos. PLoS Genet. 2022 Nov;18(11):e1010459
Assay type:	Western blot
MGI Accession ID:	MGI:7410866
Gene symbol:	Prkdc
Gene name:	protein kinase, DNA activated, catalytic polypeptide

Antibody:

anti-DNA-PKcs

Results

Image: 4B DNA-PKcs ©

	Sample Information		Bands	Other Sample Information
Lane	Age	Structure	Size Not Specified	Genetic Background	Mutant Allele(s)	Sex
1	E12.5	TS20: liver	Present	Not Specified		Not Specified
2	E12.5	TS20: liver	Strong	involves: 129/Sv * C57BL/6	Fancd2^{Gt(OST57859)Lex}/Fancd2^{Gt(OST57859)Lex}	Not Specified
3	E12.5	TS20: liver	Present	involves: 129	Smad3^tm1Par/Smad3^tm1Par	Not Specified
4	E12.5	TS20: liver	Present	involves: 129/Sv * C57BL/6	Fancd2^{Gt(OST57859)Lex}/Fancd2^{Gt(OST57859)Lex}, Smad3^tm1Par/Smad3^tm1Par	Not Specified
5	E12.5	TS20: liver	Strong (a)	involves: 129/Sv * C57BL/6	Fancd2^{Gt(OST57859)Lex}/Fancd2^{Gt(OST57859)Lex}, Smad3^tm1Par/Smad3^tm1Par	Not Specified
6	E12.5	TS20: liver	Present	involves: 129/Sv * C57BL/6	Fancd2^{Gt(OST57859)Lex}/Fancd2^{Gt(OST57859)Lex}, Smad3^tm1Par/Smad3^tm1Par	Not Specified
7	E12.5	TS20: liver	Present	involves: 129/Sv * C57BL/6	Fancd2^{Gt(OST57859)Lex}/Fancd2^{Gt(OST57859)Lex}, Smad3^tm1Par/Smad3^tm1Par	Not Specified
8	E12.5	TS20: liver	Ambiguous	Not Specified		Not Specified
9	E12.5	TS20: liver	Ambiguous	involves: 129/Sv * C57BL/6	Fancd2^{Gt(OST57859)Lex}/Fancd2^{Gt(OST57859)Lex}	Not Specified
10	E12.5	TS20: liver	Ambiguous	involves: 129	Smad3^tm1Par/Smad3^tm1Par	Not Specified
11	E12.5	TS20: liver	Present	involves: 129/Sv * C57BL/6	Fancd2^{Gt(OST57859)Lex}/Fancd2^{Gt(OST57859)Lex}, Smad3^tm1Par/Smad3^tm1Par	Not Specified
12	E12.5	TS20: liver	Present	involves: 129/Sv * C57BL/6	Fancd2^{Gt(OST57859)Lex}/Fancd2^{Gt(OST57859)Lex}, Smad3^tm1Par/Smad3^tm1Par	Not Specified

Notes:
(a) Subset of Smad3 Fancd2-129B6F2 embryos with high levels of phospho-ERK1/2 have increased levels of DNA-PKcs expression.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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