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Gene Expression Data
Assay Details
Assay
Reference: J:329537 Martinez Traverso IM, et al., LATS1/2 control TGFB-directed epithelial-to-mesenchymal transition in the murine dorsal cranial neuroepithelium through YAP regulation. Development. 2022 Sep 15;149(18):dev200860
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7408389
Gene symbol: Yap1
Gene name: yes-associated protein 1
Results
Specimen 2A Control (left): embryonic day 10.5; Lats1tm1.1Jfm/?, Lats2tm1.1Jfm/? (more )
Structure Level Pattern Image Note
TS17: brain Present 2A Control (left)
Specimen 2A Control (right): embryonic day 10.5; Lats1tm1.1Jfm/?, Lats2tm1.1Jfm/? (more )
Structure Level Pattern Image Note
TS17: branchial arch Present 2A Control (right)
Specimen 2A DCKO (left): embryonic day 10.5; E2f1Tg(Wnt1-cre)2Sor/0, Lats1tm1.1Jfm/Lats1tm1.1Jfm, Lats2tm1.1Jfm/Lats2tm1.1Jfm (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: brain Absent 2A DCKO (left) Expression not detected in neuroepithelium.
Specimen 2A DCKO (right): embryonic day 10.5; E2f1Tg(Wnt1-cre)2Sor/0, Lats1tm1.1Jfm/Lats1tm1.1Jfm, Lats2tm1.1Jfm/Lats2tm1.1Jfm (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: branchial arch Absent 2A DCKO (right)
TS17: head Present Regionally restricted 2A DCKO (right) Expression unaltered in non-neuroepithelium-derived tissues.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory