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Gene Expression Data
Assay Details
Assay
Reference: J:326033 Kim M, et al., Synovial joint cavitation initiates with microcavities in interzone and is coupled to skeletal flexion and elongation in developing mouse embryo limbs. Biol Open. 2022 Jun 15;11(6):bio059381
Assay type: RNA in situ
MGI Accession ID: MGI:7408252
Gene symbol: Has2
Gene name: hyaluronan synthase 2
Probe: Mm-Has2 (465171)
Probe preparation: Antisense RNA
Results
Specimen 4 E14.5 control: embryonic day 14.5; Has2tm1.1Yama/Has2+ (more )
Structure Level Pattern Image Note
TS22: hindlimb joint Strong 6B-1
Specimen 4 E14.5 cKO: embryonic day 14.5; Has2tm1.1Yama/Has2tm1.1Yama, Tg(Gdf5-cre,-ALPP)1Kng/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: hindlimb joint Trace 6B-2 Expression was effectively ablated in the mutant.
Specimen 4 E15.5 control: embryonic day 15.5; Has2tm1.1Yama/Has2+ (more )
Structure Level Pattern Image Note
TS23: hindlimb joint Strong 6B-3
Specimen 4 E15.5 cKO: embryonic day 15.5; Has2tm1.1Yama/Has2tm1.1Yama, Tg(Gdf5-cre,-ALPP)1Kng/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: hindlimb joint Weak 6B-4 Expression was effectively ablated in the mutant.
Specimen 4 E16.5 control: embryonic day 16.5; Has2tm1.1Yama/Has2+ (more )
Structure Level Pattern Image Note
TS24: knee joint Present 6B-5 Decreased expression.
Specimen 4 E16.5 cKO: embryonic day 16.5; Has2tm1.1Yama/Has2tm1.1Yama, Tg(Gdf5-cre,-ALPP)1Kng/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: knee joint Weak 6B-6 Expression was effectively ablated in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory