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Gene Expression Data
Assay Details
Assay
Reference: J:326033 Kim M, et al., Synovial joint cavitation initiates with microcavities in interzone and is coupled to skeletal flexion and elongation in developing mouse embryo limbs. Biol Open. 2022 Jun 15;11(6):bio059381
Assay type: RNA in situ
MGI Accession ID: MGI:7408251
Gene symbol: Prg4
Gene name: proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
Probe: Mm-Prg4 (437661)
Probe preparation: Antisense RNA
Results
Specimen 4 E14.5 control: embryonic day 14.5; Has2tm1.1Yama/Has2+ (more )
Structure Level Pattern Image Note
TS22: hindlimb joint Weak 6C-1
Specimen 4 E14.5 cKO: embryonic day 14.5; Has2tm1.1Yama/Has2tm1.1Yama, Tg(Gdf5-cre,-ALPP)1Kng/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: hindlimb joint Weak 6C-2
Specimen 4 E15.5 control: embryonic day 15.5; Has2tm1.1Yama/Has2+ (more )
Structure Level Pattern Image Note
TS23: hindlimb joint Weak 6C-3
Specimen 4 E15.5 cKO: embryonic day 15.5; Has2tm1.1Yama/Has2tm1.1Yama, Tg(Gdf5-cre,-ALPP)1Kng/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: hindlimb joint Weak 6C-4
Specimen 4 E16.5 control: embryonic day 16.5; Has2tm1.1Yama/Has2+ (more )
Structure Level Pattern Image Note
TS24: knee joint Present 6C-5 Stronger expression.
Specimen 4 E16.5 cKO: embryonic day 16.5; Has2tm1.1Yama/Has2tm1.1Yama, Tg(Gdf5-cre,-ALPP)1Kng/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: knee joint Present 6C-6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory