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Gene Expression Data
Assay Details
Assay
Reference: J:52528 Davies JM, et al., Novel BTB/POZ domain zinc-finger protein, LRF, is a potential target of the LAZ-3/BCL-6 oncogene. Oncogene. 1999 Jan 14;18(2):365-75
Assay type: RNA in situ
MGI Accession ID: MGI:7408142
Gene symbol: Zbtb7a
Gene name: zinc finger and BTB domain containing 7a
Probe: Lrf cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Assay notes: Authors note that otocyst staining was artefactual.
Results
Specimen 3C 1: embryonic day 9.5-10.0 (more )
Note: Specimen C 1 was a slightly earlier developmental stage than specimen C 2.
Structure Level Pattern Image Note
TS16: 1st branchial arch mandibular component Present 3C 1
TS16: 1st branchial arch maxillary component Present 3C 1
TS16: 2nd branchial arch Present 3C 1
TS16: tail Present 3C 1
TS16: extraembryonic component Present 3C 1 Expression was detected in the placenta.
TS16: forelimb bud Present Diffuse 3C 1 In the forelimb bud, the highest level of staining was observed around a distal rim and gradually decreased into the more proximal tissues, suggesting that the expression increases along the proximo-distal axis.
TS16: forelimb bud apical ectodermal ridge Present 3C 1 Expression in the forelimb bud was highest in the apical ectodermal ridge.
TS16: forelimb bud mesenchyme Present Regionally restricted 3C 1 Expression was detected in the progress zone mesenchyme with a slight bias towards the posterior aspect of the forelimb bud.
TS16: hindlimb bud Strong Regionally restricted 3C 1 Expression was detected at the posterior margin.
TS16: neural tube Weak Regionally restricted 3C 1 Low level expression was detected in the ventral neural tube.
Specimen 3C 2: embryonic day 9.5-10.0 (more )
Note: Specimen C 1 was a slightly earlier developmental stage than specimen C 2.
Structure Level Pattern Image Note
TS16: 1st branchial arch mandibular component Present 3C 2
TS16: 1st branchial arch maxillary component Present 3C 2
TS16: 2nd branchial arch Present 3C 2
TS16: umbilical cord Present 3C 2
TS16: forelimb bud Present Diffuse 3C 2 In the forelimb bud, the highest level of staining was observed around a distal rim and gradually decreased into the more proximal tissues, suggesting that the expression increases along the proximo-distal axis.
TS16: forelimb bud apical ectodermal ridge Present 3C 2 Expression in the forelimb bud was highest in the apical ectodermal ridge.
TS16: forelimb bud mesenchyme Present Regionally restricted 3C 2 Expression was detected in the progress zone mesenchyme with a slight bias towards the posterior aspect of the forelimb bud.
TS16: hindlimb bud Present Regionally restricted 3C 2 Expression in this specimen was diffuse, but still biased to the posterior (top left) side of the bud.
TS16: neural tube Weak Regionally restricted 3C 2 Low level expression was detected in the ventral neural tube.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory