Tg(Emu-RET)385Ina
Transgene Detail
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| Symbol: |
Tg(Emu-RET)385Ina |
| Name: |
transgene insertion 385, Izumi Nakashima |
| MGI ID: |
MGI:7398501 |
| Synonyms: |
E-mu-ret, Emu-ret |
| Transgene: |
Tg(Emu-RET)385Ina Location: unknown
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| Alliance: |
Tg(Emu-RET)385Ina page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Emu-RET)385Ina expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
RET (5979) |
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Expresses transforming mutant cDNA |
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Mutation details: A human transforming RET cDNA was isolated from a cDNA library of a THP-1 human monocytic leukemia cell line in which the sequences encoding the last 51 carboxy-terminal amino acids of the ret proto-oncogene were replaced with sequences encoding 9 unrelated amino acids. This cDNA was expressed under the control of the Emu enhancer (Rr150) from the immunoglobulin heavy chain (Igh) gene.
(J:276582)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:276582 Iwamoto T, et al., Preferential development of pre-B lymphomas with drastically down-regulated N-myc in the E mu-ret transgenic mice. Eur J Immunol. 1991 Aug;21(8):1809-14 |
| All: |
9 reference(s) |
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Analysis Tools
